| Gene Symbol |
GGA2
|
| Entrez Gene |
23062
|
| Alt Symbol |
VEAR
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
golgi-associated, gamma adaptin ear containing, ARF binding protein 2
|
| Other Description |
ADP-ribosylation factor-binding protein GGA2|VHS domain and ear domain of gamma-adaptin|VHS domain and ear domain-containing protein|gamma-adaptin-related protein 2|golgi associated, gamma adaptin ear containing, ARF binding protein 2|golgi-localized, gamma ear-containing, ARF-binding protein 2
|
| Swissprots |
Q9UPS2 Q9UJY4 O14564 D3DWF0 Q9NYN2
|
| Accessions |
AAC05813 EAW55827 EAW55828 EAW55829 Q9UJY4 AB029003 BAA83032 AF165531 AAF42806 AF190863 AAF05708 AF233522 AAF35394 AF323754 AAK38634 AK024619 AK026350 AK093769 AK308425 BC000284 AAH00284 BC050620 BU689580 BU855556 CN423115 DA439738 DQ892534 ABM83460 DQ895745 ABM86671 XM_011545771 XP_011544073 NM_015044 NP_055859
|
| Function |
Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF- dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif.
|
| Subcellular Location |
Golgi apparatus, trans-Golgi network membrane {ECO:0000269|PubMed:15039775}; Peripheral membrane protein {ECO:0000269|PubMed:15039775}. Endosome membrane {ECO:0000269|PubMed:15039775}; Peripheral membrane protein {ECO:0000269|PubMed:15039775}.
|
| Tissue Specificity |
Ubiquitously expressed.
|
| Top Pathways |
Lysosome
|