Gene Symbol | PIGO |
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Entrez Gene | 84720 |
Alt Symbol | HPMRS2 |
Species | Human |
Gene Type | protein-coding |
Description | phosphatidylinositol glycan anchor biosynthesis, class O |
Other Description | GPI ethanolamine phosphate transferase 3|phosphatidylinositol-glycan biosynthesis class O protein |
Swissprots | Q8TDS8 Q9BVN9 Q9Y4B0 Q6UX80 Q6P154 B1AML3 Q8TEQ8 Q96CS9 |
Accessions | AAC07985 BAB89338 EAW58397 EAW58398 EAW58399 EAW58400 Q8TEQ8 AK074064 BAB84890 AK090433 BAC03414 AL833956 CAD38806 AW149348 AY358472 AAQ88836 BC001030 AAH01030 BC013987 AAH13987 BC029271 AAH29271 BC036916 AAH36916 BC065282 AAH65282 BE139632 BI818120 BU727886 CD387014 CR985224 CR991745 DQ575362 XM_005251619 XP_005251676 XM_011518056 XP_011516358 XR_242515 NM_001201484 NP_001188413 NM_032634 NP_116023 NM_152850 NP_690577 |
Function | Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the GPI third mannose which links the GPI-anchor to the C-terminus of the proteins by an amide bond (By similarity). {ECO:0000250}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
Top Pathways | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis |
PIG-O CRISPR/Cas9 KO Plasmid (h) - sc-417597 from Santa Cruz Biotechnology
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PIG-O HDR Plasmid (h) - sc-417597-HDR from Santa Cruz Biotechnology
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PIG-O Double Nickase Plasmid (h) - sc-417597-NIC from Santa Cruz Biotechnology
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PIG-O Double Nickase Plasmid (h2) - sc-417597-NIC-2 from Santa Cruz Biotechnology
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PIG-O CRISPR Activation Plasmid (h) - sc-417597-ACT from Santa Cruz Biotechnology
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PIG-O CRISPR Activation Plasmid (h2) - sc-417597-ACT-2 from Santa Cruz Biotechnology
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PIG-O Lentiviral Activation Particles (h) - sc-417597-LAC from Santa Cruz Biotechnology
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PIG-O Lentiviral Activation Particles (h2) - sc-417597-LAC-2 from Santa Cruz Biotechnology
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PIG-O siRNA (h) - sc-92756 from Santa Cruz Biotechnology
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PIG-O shRNA Plasmid (h) - sc-92756-SH from Santa Cruz Biotechnology
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PIG-O shRNA (h) Lentiviral Particles - sc-92756-V from Santa Cruz Biotechnology
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PIGO RNAi - H00084720-R01 from Novus Biologicals
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MISSION® esiRNA - EHU094281 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN16792 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16792 from Sigma-Aldrich
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PIGO siRNA (Human) - CRJ3600 from Cohesion Biosciences
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PIGO RNAi - H00084720-R02 from Novus Biologicals
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shRNA set against Human PIGO (NM_032634.3) - SHH375468 from Creative biogene
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Human PIGO siRNA - orb274101 from Biorbyt
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PIGO shRNA Plasmid (Human) - CHJ3600 from Cohesion Biosciences
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PIGO miRNA 3'UTR clone - MiUTR3H-13376 from Creative biogene
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PIGO miRNA 3'UTR clone - MiUTR3H-13377 from Creative biogene
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