Gene Symbol | CHRNB3 |
---|---|
Entrez Gene | 1142 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | cholinergic receptor, nicotinic, beta 3 (neuronal) |
Other Description | acetylcholine receptor, neuronal nicotinic, beta-3 subunit|acetylcholine receptor, nicotinic, beta 3 (neuronal)|cholinergic receptor, nicotinic, beta polypeptide 3|neuronal acetylcholine receptor subunit beta-3 |
Swissprots | Q05901 Q15827 |
Accessions | AAD33063 EAW63208 Q05901 BC069681 AAH69681 BC069703 AAH69703 BC069788 AAH69788 HQ447438 ADQ31924 U62438 AAB40116 X67513 CAA47851 Y08417 CAA69694 XM_011544390 XP_011542692 NM_000749 NP_000740 |
Function | After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. |
Subcellular Location | Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. |
Top Pathways | Neuroactive ligand-receptor interaction |