| Gene Symbol |
REPIN1
|
| Entrez Gene |
29803
|
| Alt Symbol |
AP4, RIP60, ZNF464, Zfp464
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
replication initiator 1
|
| Other Description |
60 kDa origin-specific DNA-binding protein|60 kDa replication initiation region protein|ATT-binding protein|DHFR oribeta-binding protein RIP60|H_DJ0584D14.12|replication initiation region protein (60kD)|zinc finger protein 464 (RIP60)|zinc finger protein AP4
|
| Swissprots |
C9J3L7 Q9UMP5 D3DWZ1 Q9BUZ6 Q7LE03 Q9NZH2 Q9BWE0
|
| Accessions |
AAS00385 AAS00386 EAL24474 EAL24475 EAW54113 EAW54114 EAW54117 EAW54118 EAW54119 Q9BWE0 AF201303 AAF26712 AJ245553 CAB53100 AK025356 AK225227 AK226081 AK292670 BAF85359 AL046625 BC000363 AAH00363 BC001760 AAH01760 CA449524 CN386958 CX166683 CX756128 DB161182 DQ582093 DQ594555 EU446796 ABZ92325 XM_005249985 XP_005250042 XM_006715947 XP_006716010 XM_006715948 XP_006716011 XM_006715949 XP_006716012 XM_006715950 XP_006716013 XM_006715951 XP_006716014 XM_006715952 XP_006716015 XM_006715953 XP_006716016 XM_011516111 XP_011514413 XM_011516112 XP_011514414 NM_001099695 NP_001093165 NM_001099696 NP_001093166 NM_013400 NP_037532 NM_014374 NP_055189
|
| Function |
Sequence-specific double-stranded DNA-binding protein required for initiation of chromosomal DNA replication. Binds on 5'-ATT-3' reiterated sequences downstream of the origin of bidirectional replication (OBR) and a second, homologous ATT sequence of opposite orientation situated within the OBR zone. Facilitates DNA bending.
|
| Subcellular Location |
Nucleus {ECO:0000269|PubMed:10606657}.
|