Gene Symbol | HOGA1 |
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Entrez Gene | 112817 |
Alt Symbol | C10orf65, DHDPS2, DHDPSL, HP3, NPL2 |
Species | Human |
Gene Type | protein-coding |
Description | 4-hydroxy-2-oxoglutarate aldolase 1 |
Other Description | 4-hydroxy-2-oxoglutarate aldolase, mitochondrial|DHDPS-like protein|N-acetylneuraminate pyruvate lyase 2 (putative)|dihydrodipicolinate synthase-like, mitochondrial|dihydrodipicolinate synthetase homolog 2|probable 2-keto-4-hydroxyglutarate aldolase|probable 4-hydroxy-2-oxoglutarate aldolase, mitochondrial|probable KHG-aldolase|protein 569272 |
Swissprots | Q8N9F2 Q86XE5 Q711P0 A8K075 Q96EV5 Q5T680 Q5T684 |
Accessions | CAC84901 EAW49912 EAW49913 EAW49914 Q86XE5 AK094791 AK289440 BAF82129 BC011916 AAH11916 BC045550 AAH45550 BC057821 AAH57821 EU831607 ACE87207 EU831618 ACE87218 EU831694 ACE86528 EU831704 ACE86538 HQ448020 ADQ32501 NM_001134670 NP_001128142 NM_138413 NP_612422 |
Function | Catalyzes the final step in the metabolic pathway of hydroxyproline. {ECO:0000269|PubMed:20797690, ECO:0000269|PubMed:21998747}. |
Subcellular Location | Mitochondrion {ECO:0000250}. |
Top Pathways | Arginine and proline metabolism, Glyoxylate and dicarboxylate metabolism |
DHDPSL CRISPR/Cas9 KO Plasmid (h) - sc-410248 from Santa Cruz Biotechnology
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DHDPSL HDR Plasmid (h) - sc-410248-HDR from Santa Cruz Biotechnology
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DHDPSL Double Nickase Plasmid (h) - sc-410248-NIC from Santa Cruz Biotechnology
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DHDPSL Double Nickase Plasmid (h2) - sc-410248-NIC-2 from Santa Cruz Biotechnology
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DHDPSL CRISPR Activation Plasmid (h) - sc-410248-ACT from Santa Cruz Biotechnology
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DHDPSL CRISPR Activation Plasmid (h2) - sc-410248-ACT-2 from Santa Cruz Biotechnology
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DHDPSL Lentiviral Activation Particles (h) - sc-410248-LAC from Santa Cruz Biotechnology
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DHDPSL Lentiviral Activation Particles (h2) - sc-410248-LAC-2 from Santa Cruz Biotechnology
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DHDPSL siRNA (h) - sc-90602 from Santa Cruz Biotechnology
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DHDPSL shRNA Plasmid (h) - sc-90602-SH from Santa Cruz Biotechnology
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DHDPSL siRNA (h) - sc-90620 from Santa Cruz Biotechnology
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DHDPSL shRNA Plasmid (h) - sc-90620-SH from Santa Cruz Biotechnology
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DHDPSL shRNA (h) Lentiviral Particles - sc-90620-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU133461 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10216 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10216 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR08656 from Sigma-Aldrich
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HOGA1 siRNA (Human) - CRJ4293 from Cohesion Biosciences
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HOGA1 - MBS8214625 from MyBioSource
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shRNA set against Human HOGA1 (NM_138413.3) - SHH313941 from Creative biogene
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Human HOGA1 siRNA - orb274794 from Biorbyt
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HOGA1 shRNA Plasmid (Human) - CHJ4293 from Cohesion Biosciences
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HOGA1 miRNA 3'UTR clone - MiUTR4H-TG02708 from Creative biogene
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