| Gene Symbol |
DUX4L9
|
| Entrez Gene |
100288711
|
| Alt Symbol |
DUX4C
|
| Species |
Human
|
| Gene Type |
pseudo
|
| Description |
double homeobox 4 like 9
|
| Other Description |
double homeobox 4 like 9 (pseudogene)|double homeobox 4 pseudogene|double homeobox 4c
|
| Swissprots |
Q6RFH8
|
| Accessions |
AAA87408 AAS15569 NM_001023569 NM_001099853
|
| Function |
May be involved in transcriptional regulation (By similarity). Down-regulates MYOD1 expression and may up-regulate MYF5 expression. May regulate microRNA (miRNA) transcription, upregulating the expression of some myogenic miRNAs, including MIR1-1, MIR133A2, MIR133B and MIR206. Impairs the differentiation of myoblasts and may be involved in muscle regeneration. {ECO:0000250, ECO:0000269|PubMed:18723017, ECO:0000269|PubMed:19829708, ECO:0000269|PubMed:24145033}.
|
| Subcellular Location |
Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108, ECO:0000269|PubMed:19829708}.
|
| Tissue Specificity |
Expressed in muscles, as well as in primary myoblasts and myotubes (at protein level). {ECO:0000269|PubMed:19829708}.
|
