Gene Symbol | SCYL3 |
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Entrez Gene | 57147 |
Alt Symbol | PACE-1, PACE1 |
Species | Human |
Gene Type | protein-coding |
Description | SCY1-like 3 (S. cerevisiae) |
Other Description | SCY1-like protein 3|ezrin-binding partner PACE-1 (PACE-1)|ezrin-binding protein PACE-1|protein-associating with the carboxyl-terminal domain of ezrin |
Swissprots | Q8IZN9 Q96C56 Q5THA6 Q9UBK6 Q5THA8 Q8IZE3 A8K8Z2 |
Accessions | EAW90867 EAW90868 Q8IZE3 AA844031 AF540957 AAN23123 AK292507 BAF85196 AK304481 BAG65292 AL117233 CAB55300 AM393842 CAL38717 AY144493 AAN41656 BC014662 AAH14662 BX647352 DA449356 DB285397 DQ893468 ABM84394 DQ896344 ABM87343 XM_006711465 XP_006711528 XM_006711467 XP_006711530 XM_011509801 XP_011508103 XM_011509802 XP_011508104 XM_011509803 XP_011508105 NM_020423 NP_065156 NM_181093 NP_851607 |
Function | May play a role in regulating cell adhesion/migration complexes in migrating cells. {ECO:0000269|PubMed:12651155}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:12651155}. Golgi apparatus {ECO:0000269|PubMed:12651155}. Cell projection, lamellipodium {ECO:0000269|PubMed:12651155}. Note=Colocalized with EZR/VIL2, actin and CD44 in lamellipodia. |
Tissue Specificity | Ubiquitously expressed. {ECO:0000269|PubMed:12651155}. |
SCYL3 CRISPR/Cas9 KO Plasmid (h) - sc-412765 from Santa Cruz Biotechnology
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SCYL3 HDR Plasmid (h) - sc-412765-HDR from Santa Cruz Biotechnology
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SCYL3 Double Nickase Plasmid (h) - sc-412765-NIC from Santa Cruz Biotechnology
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SCYL3 Double Nickase Plasmid (h2) - sc-412765-NIC-2 from Santa Cruz Biotechnology
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SCYL3 CRISPR Activation Plasmid (h) - sc-412765-ACT from Santa Cruz Biotechnology
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SCYL3 CRISPR Activation Plasmid (h2) - sc-412765-ACT-2 from Santa Cruz Biotechnology
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SCYL3 Lentiviral Activation Particles (h) - sc-412765-LAC from Santa Cruz Biotechnology
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SCYL3 Lentiviral Activation Particles (h2) - sc-412765-LAC-2 from Santa Cruz Biotechnology
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SCYL3 siRNA (h) - sc-88316 from Santa Cruz Biotechnology
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SCYL3 shRNA Plasmid (h) - sc-88316-SH from Santa Cruz Biotechnology
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SCYL3 shRNA (h) Lentiviral Particles - sc-88316-V from Santa Cruz Biotechnology
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SCY1 like 3 RNAi - H00057147-R03 from Novus Biologicals
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MISSION® esiRNA - EHU080231 from Sigma-Aldrich
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MISSION® siRNA - SIHK2054 from Sigma-Aldrich
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MISSION® siRNA - SIHK2052 from Sigma-Aldrich
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MISSION® siRNA - SIHK2053 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN18982 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18982 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05688 from Sigma-Aldrich
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SCYL3 siRNA (Human) - CRJ1356 from Cohesion Biosciences
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SCY1 like 3 RNAi - H00057147-R04 from Novus Biologicals
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SCYL3 - MBS828068 from MyBioSource
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shRNA set against Human SCYL3 (NM_181093.3) - SHH403216 from Creative biogene
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Human SCYL3 siRNA - orb271857 from Biorbyt
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SCYL3 shRNA Plasmid (Human) - CHJ1356 from Cohesion Biosciences
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