Gene Symbol | PPFIA4 |
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Entrez Gene | 8497 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 |
Other Description | liprin-alpha-4 |
Swissprots | O75335 A2RUJ5 B1APN8 B1N949 B7ZM43 O94971 |
Accessions | EAW91459 EAW91460 EAW91461 EAW91462 O75335 AB020704 BAA74920 AF034801 AAC26102 AI341415 AK023365 BAG51184 AK124535 BAG54050 AK126185 AK126624 BAC86617 AK295757 BAG58587 AL540093 BC132923 AAI32924 BC132925 AAI32926 BC144262 AAI44263 DA327222 EF428334 ABR09268 XM_006711584 XP_006711647 XM_006711585 XP_006711648 XM_006711586 XP_006711649 XM_006711587 XP_006711650 XM_006711588 XP_006711651 XM_006711589 XP_006711652 XM_006711591 XP_006711654 XM_011510069 XP_011508371 XM_011510070 XP_011508372 XM_011510071 XP_011508373 XR_426801 XR_426802 XR_426803 XR_426804 XR_921979 NM_015053 NM_001304331 NP_001291260 NM_001304332 NP_001291261 |
Function | May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Cell surface {ECO:0000250}. Note=Colocalizes with PTPRF at the cell surface. {ECO:0000250}. |
Tissue Specificity | Expressed only in the heart, brain, and skeletal muscle. {ECO:0000269|PubMed:9624153}. |
Liprin α4 CRISPR/Cas9 KO Plasmid (h) - sc-411182 from Santa Cruz Biotechnology
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Liprin α4 HDR Plasmid (h) - sc-411182-HDR from Santa Cruz Biotechnology
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Liprin α4 Double Nickase Plasmid (h) - sc-411182-NIC from Santa Cruz Biotechnology
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Liprin α4 Double Nickase Plasmid (h2) - sc-411182-NIC-2 from Santa Cruz Biotechnology
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Liprin α4 CRISPR Activation Plasmid (h) - sc-411182-ACT from Santa Cruz Biotechnology
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Liprin α4 CRISPR Activation Plasmid (h2) - sc-411182-ACT-2 from Santa Cruz Biotechnology
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Liprin α4 Lentiviral Activation Particles (h) - sc-411182-LAC from Santa Cruz Biotechnology
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Liprin α4 Lentiviral Activation Particles (h2) - sc-411182-LAC-2 from Santa Cruz Biotechnology
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Liprin α4 siRNA (h) - sc-105616 from Santa Cruz Biotechnology
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Liprin α4 shRNA Plasmid (h) - sc-105616-SH from Santa Cruz Biotechnology
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Liprin α4 shRNA (h) Lentiviral Particles - sc-105616-V from Santa Cruz Biotechnology
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MISSION® Human Phosphatase - SIHP0473 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0472 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0474 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17215 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17215 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR12906 from Sigma-Aldrich
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PPFIA4 siRNA (Human) - CRH5571 from Cohesion Biosciences
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PPFIA4 RNAi - H00008497-R01 from Novus Biologicals
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shRNA set against Human PPFIA4 (NM_015053.1) - SHH380508 from Creative biogene
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Human PPFIA4 siRNA - orb266073 from Biorbyt
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PPFIA4 shRNA Plasmid (Human) - CHH5571 from Cohesion Biosciences
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PPFIA4 miRNA 3'UTR clone - MiUTR1H-08144 from Creative biogene
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