| Gene Symbol |
Ak6
|
| Entrez Gene |
102216272
|
| Alt Symbol |
2810046E22Rik, 4921516M08Rik, AK/ATPase
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
adenylate kinase 6
|
| Other Description |
AK/ATPase|ATP-AMP transphosphorylase 6|adenylate kinase isoenzyme 6|coilin-interacting nuclear ATPase protein|dual activity adenylate kinase/ATPase
|
| Swissprots |
Q8VCP8
|
| Accessions |
EDL00800 EDL00801 Q8VCP8 AK012905 AK014903 AU045423 BC019453 AAH19453 BG084768 CR516570 NM_027592 NP_081868
|
| Function |
Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation. {ECO:0000255|HAMAP-Rule:MF_03173}.
|
| Subcellular Location |
Nucleus, nucleoplasm {ECO:0000255|HAMAP- Rule:MF_03173}. Nucleus, Cajal body {ECO:0000255|HAMAP- Rule:MF_03173}. Note=Displays widespread diffuse nucleoplasmic distribution but not detected in nucleoli. Detected in Cajal bodies but not in all cells. {ECO:0000255|HAMAP-Rule:MF_03173}.
|
| Top Pathways |
Ribosome biogenesis in eukaryotes, Purine metabolism
|