Gene Symbol | NDUFC1 |
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Entrez Gene | 4717 |
Alt Symbol | KFYI |
Species | Human |
Gene Type | protein-coding |
Description | NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa |
Other Description | CI-KFYI|NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial|NADH-ubiquinone oxidoreductase KFYI subunit|complex I KFYI subunit|complex I-KFYI |
Swissprots | O43677 Q3MIJ9 A8K532 |
Accessions | AAY40949 EAX05121 O43677 AF047184 AAC04269 AF047435 AAC39886 AK023115 AK291147 BAF83836 BC101798 AAI01799 BC107682 AAI07683 BC112061 AAI12062 BG701467 BM768825 BU677336 CA313899 CB047240 CB160001 CN347371 CR457005 CAG33286 CX163301 W56292 NM_001184986 NP_001171915 NM_001184987 NP_001171916 NM_001184988 NP_001171917 NM_001184989 NP_001171918 NM_001184990 NP_001171919 NM_001184991 NP_001171920 NM_002494 NP_002485 |
Function | Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. |
Subcellular Location | Mitochondrion inner membrane; Single-pass membrane protein; Matrix side. |
Top Pathways | Alzheimer's disease, Huntington's disease, Non-alcoholic fatty liver disease (NAFLD), Oxidative phosphorylation |
NDUFC1 CRISPR/Cas9 KO Plasmid (h) - sc-410903 from Santa Cruz Biotechnology
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NDUFC1 HDR Plasmid (h) - sc-410903-HDR from Santa Cruz Biotechnology
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NDUFC1 Double Nickase Plasmid (h) - sc-410903-NIC from Santa Cruz Biotechnology
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NDUFC1 Double Nickase Plasmid (h2) - sc-410903-NIC-2 from Santa Cruz Biotechnology
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NDUFC1 CRISPR Activation Plasmid (h) - sc-410903-ACT from Santa Cruz Biotechnology
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NDUFC1 CRISPR Activation Plasmid (h2) - sc-410903-ACT-2 from Santa Cruz Biotechnology
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NDUFC1 Lentiviral Activation Particles (h) - sc-410903-LAC from Santa Cruz Biotechnology
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NDUFC1 Lentiviral Activation Particles (h2) - sc-410903-LAC-2 from Santa Cruz Biotechnology
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NDUFC1 siRNA (h) - sc-89153 from Santa Cruz Biotechnology
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NDUFC1 shRNA Plasmid (h) - sc-89153-SH from Santa Cruz Biotechnology
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NDUFC1 shRNA (h) Lentiviral Particles - sc-89153-V from Santa Cruz Biotechnology
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NDUFC1 RNAi - H00004717-R01 from Novus Biologicals
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MISSION® esiRNA - EHU058731 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN15164 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15164 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01366 from Sigma-Aldrich
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NDUFC1 siRNA (Human) - CRH3131 from Cohesion Biosciences
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shRNA set against Human NDUFC1 (NM_002494.3) - SHH350816 from Creative biogene
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Human NDUFC1 siRNA - orb263633 from Biorbyt
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NDUFC1 shRNA Plasmid (Human) - CHH3131 from Cohesion Biosciences
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NDUFC1 miRNA 3'UTR clone - MiUTR4H-TG05937 from Creative biogene
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