Gene Symbol |
SLC38A5
|
Entrez Gene |
92745
|
Alt Symbol |
JM24, SN2, SNAT5, pp7194
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
solute carrier family 38, member 5
|
Other Description |
sodium-coupled neutral amino acid transporter 5|solute carrier family 38 (amino acid transporter), member 5|system N transporter 2|transport system N, protein 2
|
Swissprots |
B7WPJ9 Q8WUX1 Q8WYU2 Q96PQ4 B5MDE6 B3KT20 Q6PIW9
|
Accessions |
EAW50785 EAW50786 EAW50787 EAW50788 EAW50789 EAW50790 Q8WUX1 AF276889 AAK61856 AF318358 AAL55865 AK094788 BAG52932 AW183216 BC019246 AAH19246 BC027721 AAH27721 DA089769 DQ893060 ABM83986 DQ896312 ABM87311 XM_005272694 XP_005272751 XM_005272695 XP_005272752 XM_005272697 XP_005272754 XM_005272698 XP_005272755 XM_006724569 XP_006724632 NM_033518 NP_277053
|
Function |
Functions as a sodium-dependent amino acid transporter which countertransport protons. Mediates the saturable, pH- sensitive, and electrogenic cotransport of several neutral amino acids including glycine, asparagine, alanine, serine, glutamine and histidine with sodium. {ECO:0000269|PubMed:11243884}.
|
Subcellular Location |
Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
|
Tissue Specificity |
Predominantly expressed in stomach, brain, liver, lung and intestinal tract. {ECO:0000269|PubMed:11243884}.
|
Top Pathways |
GABAergic synapse
|