SEMA6D
| Gene Symbol | SEMA6D |
|---|---|
| Entrez Gene | 80031 |
| Alt Symbol | - |
| Species | Human |
| Gene Type | protein-coding |
| Description | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D |
| Other Description | semaphorin-6D |
| Swissprots | Q9P249 Q8NFY7 A7E2A0 Q8NFY6 Q8NFY3 Q8NFY5 A6NM95 Q8NFY4 A6NF10 A6NNK1 |
| Accessions | CAI48006 CAT82582 CAT82584 CAT82585 CAT82587 CAT82590 CAT82592 EAW77332 EAW77333 Q8NFY4 AB040912 BAA96003 AF389426 AAM69449 AF389427 AAM69450 AF389428 AAM69451 AF389429 AAM69452 AF389430 AAM69453 AK021660 BAB13869 AK022747 BAB14221 AK022831 BAB14264 AK290032 BAF82721 BC004330 BC150253 AAI50254 XM_005254685 XP_005254742 XM_005254686 XP_005254743 XM_005254687 XP_005254744 XM_005254689 XP_005254746 XM_011522075 XP_011520377 XM_011522076 XP_011520378 XM_011522077 XP_011520379 XM_011522078 XP_011520380 XM_011522079 XP_011520381 XM_011522080 XP_011520382 XM_011522081 XP_011520383 XM_011522082 XP_011520384 NM_001198999 NP_001185928 NM_020858 NP_065909 NM_024966 NP_079242 NM_153616 NP_705869 NM_153617 NP_705870 NM_153618 NP_705871 NM_153619 NP_705872 |
| Function | Shows growth cone collapsing activity on dorsal root ganglion (DRG) neurons in vitro. May be a stop signal for the DRG neurons in their target areas, and possibly also for other neurons. May also be involved in the maintenance and remodeling of neuronal connections. |
| Subcellular Location | Isoform 5: Cell membrane; Single-pass type I membrane protein. |
| Top Pathways | Axon guidance |
SEMA6D CRISPR/Cas9 KO Plasmid (h) - sc-417804 from Santa Cruz Biotechnology
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SEMA6D HDR Plasmid (h) - sc-417804-HDR from Santa Cruz Biotechnology
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SEMA6D Double Nickase Plasmid (h) - sc-417804-NIC from Santa Cruz Biotechnology
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SEMA6D Double Nickase Plasmid (h2) - sc-417804-NIC-2 from Santa Cruz Biotechnology
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SEMA6D CRISPR Activation Plasmid (h) - sc-417804-ACT from Santa Cruz Biotechnology
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SEMA6D CRISPR Activation Plasmid (h2) - sc-417804-ACT-2 from Santa Cruz Biotechnology
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SEMA6D Lentiviral Activation Particles (h) - sc-417804-LAC from Santa Cruz Biotechnology
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SEMA6D Lentiviral Activation Particles (h2) - sc-417804-LAC-2 from Santa Cruz Biotechnology
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SEMA6D siRNA (h) - sc-63008 from Santa Cruz Biotechnology
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SEMA6D shRNA Plasmid (h) - sc-63008-SH from Santa Cruz Biotechnology
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SEMA6D shRNA (h) Lentiviral Particles - sc-63008-V from Santa Cruz Biotechnology
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Semaphorin 6D RNAi - H00080031-R09 from Novus Biologicals
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Semaphorin 6D RNAi - H00080031-R10 from Novus Biologicals
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Semaphorin 6D RNAi - H00080031-R12 from Novus Biologicals
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Semaphorin 6D RNAi - H00080031-R07 from Novus Biologicals
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MISSION® esiRNA - EHU075011 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN19081 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19081 from Sigma-Aldrich
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SEMA6D siRNA (Human) - CRJ2736 from Cohesion Biosciences
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Semaphorin 6D RNAi - H00080031-R08 from Novus Biologicals
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Semaphorin 6D RNAi - H00080031-R11 from Novus Biologicals
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SEMA6D - MBS8221433 from MyBioSource
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shRNA set against Human SEMA6D (NM_024966.2) - SHH404400 from Creative biogene
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shRNA set against Human SEMA6D(NM_153618.1) - SHR214168 from Creative biogene
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shRNA set against Human SEMA6D(NM_024966.2) - SHR214192 from Creative biogene
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