Gene Symbol | SRSF8 |
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Entrez Gene | 10929 |
Alt Symbol | DSM-1, SFRS2B, SRP46 |
Species | Human |
Gene Type | protein-coding |
Description | serine/arginine-rich splicing factor 8 |
Other Description | SR splicing factor 8|pre-mRNA-splicing factor SRP46|splicing factor, arginine/serine-rich 2B|splicing factor, arginine/serine-rich, 46kD |
Swissprots | Q96TA3 Q9BRL6 B2R6B8 Q6PF01 |
Accessions | AAK54350 CAE90956 EAW66954 EAW66955 EAW66956 Q9BRL6 AF031166 AAK54351 AJ270685 AK023379 BAG51186 AK309776 AK312514 BAG35415 BC057783 AAH57783 CB215027 CV805885 DA723253 DA882851 XR_428967 NM_032102 NP_115285 NR_103726 |
Function | Involved in pre-mRNA alternative splicing. {ECO:0000269|PubMed:9671500}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:9671500}. |
Tissue Specificity | Strongly expressed in pancreas, spleen and prostate. Weakly expressed in lung, liver and thymus. {ECO:0000269|PubMed:9671500}. |
Top Pathways | Spliceosome, Herpes simplex infection |
SFRS2B CRISPR/Cas9 KO Plasmid (h) - sc-401973 from Santa Cruz Biotechnology
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SFRS2B HDR Plasmid (h) - sc-401973-HDR from Santa Cruz Biotechnology
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SFRS2B Double Nickase Plasmid (h) - sc-401973-NIC from Santa Cruz Biotechnology
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SFRS2B Double Nickase Plasmid (h2) - sc-401973-NIC-2 from Santa Cruz Biotechnology
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SFRS2B CRISPR Activation Plasmid (h) - sc-401973-ACT from Santa Cruz Biotechnology
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SFRS2B CRISPR Activation Plasmid (h2) - sc-401973-ACT-2 from Santa Cruz Biotechnology
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SFRS2B Lentiviral Activation Particles (h) - sc-401973-LAC from Santa Cruz Biotechnology
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SFRS2B Lentiviral Activation Particles (h2) - sc-401973-LAC-2 from Santa Cruz Biotechnology
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SFRS2B siRNA (h) - sc-106546 from Santa Cruz Biotechnology
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SFRS2B shRNA Plasmid (h) - sc-106546-SH from Santa Cruz Biotechnology
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SFRS2B shRNA (h) Lentiviral Particles - sc-106546-V from Santa Cruz Biotechnology
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SFRS2B RNAi - H00010929-R01 from Novus Biologicals
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MISSION® esiRNA - EHU217661 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN20607 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20607 from Sigma-Aldrich
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SRSF8 siRNA (Human) - CRH7455 from Cohesion Biosciences
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SRSF8 - MBS8227210 from MyBioSource
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shRNA set against Human SRSF8 (NM_032102.2) - SHH418268 from Creative biogene
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shRNA set against Human SFRS2B(NM_032102.2) - SHR220290 from Creative biogene
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Human SRSF8 siRNA - orb267957 from Biorbyt
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SRSF8 shRNA Plasmid (Human) - CHH7455 from Cohesion Biosciences
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SRSF8 miRNA 3'UTR clone - MiUTR1H-09332 from Creative biogene
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