Rpl13a

Gene Symbol Rpl13a
Entrez Gene 22121
Alt Symbol 1810026N22Rik, Tstap198-7, tum-antigen
Species Mouse
Gene Type protein-coding
Description ribosomal protein L13A
Other Description 60S ribosomal protein L13a|tissue specific transplantation antigen P198-7|transplantation antigen P198|tum-P198 antigen|tum-transplantation antigen P198
Swissprots P19253
Accessions CAA35908 EDL22806 P19253 AK007609 BAB25132 AK077512 AK146318 BAE27073 AK156035 BAE33555 AK159882 AK168784 BAE40618 AK168903 BAE40717 AK170030 BAE41520 AK189288 AK213140 AV445288 BC034450 BC042392 BC065799 BC082289 AAH82289 BC086896 AAH86896 CT010169 CAJ18377 NM_009438 NP_033464
Function Associated with ribosomes but is not required for canonical ribosome function and has extra-ribosomal functions (By similarity). Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma- induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma activation and subsequent phosphorylation dissociates from the ribosome and assembles into the GAIT complex which binds to stem loop- containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation. In the GAIT complex interacts with m7G cap-bound eIF4G at or near the eIF3-binding site and blocks the recruitment of the 43S ribosomal complex. {ECO:0000250, ECO:0000269|PubMed:23071094}.
Top Pathways Ribosome

60S ribosomal protein L13a (RPL13A), Mouse, ELISA Kit - E03R0435 from ARP American Research Products

Category ELISA Kit
Prices $535.00, $735.00
Sizes 48 t, 96 t
Sensitivity 0.1ng/ml
Range 0.5-10ng/ml

Mouse Rpl13a ELISA Kit - E066583 from Biobool

Category ELISA Kit
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