Gene Symbol | ATAD1 |
---|---|
Entrez Gene | 84896 |
Alt Symbol | AFDC1, FNP001, THORASE |
Species | Human |
Gene Type | protein-coding |
Description | ATPase family, AAA domain containing 1 |
Other Description | ATPase family AAA domain-containing protein 1 |
Swissprots | Q8N3G1 Q6DKG1 Q8NBU5 Q8WYR9 Q6P4B9 D3DR26 Q969Y3 |
Accessions | CAC88231 CAF86903 CBX51354 EAW50177 EAW50178 EAW50179 EAW50180 Q8NBU5 AF361493 AAL57218 AK027506 BAB55161 AK075223 BAC11482 AK304297 BAG65153 AL834370 CAD39033 BC010868 AAH10868 BC063530 AAH63530 BC073998 AAH73998 XM_005270251 XP_005270308 XM_005270252 XP_005270309 XM_005270253 XP_005270310 XM_011540302 XP_011538604 XM_011540303 XP_011538605 XM_011540304 XP_011538606 XR_945847 NM_032810 NP_116199 |
Function | ATPase that plays a critical role in regulating the surface expression of AMPA receptors (AMPAR), thereby regulating synaptic plasticity and learning and memory. Required for NMDA- stimulated AMPAR internalization and inhibition of GRIA1 and GRIA2 recycling back to the plasma membrane; these activities are ATPase-dependent (By similarity). {ECO:0000250}. |
Subcellular Location | Peroxisome {ECO:0000250}. Cell junction, synapse, postsynaptic cell membrane {ECO:0000250}. |