Gene Symbol | MPP4 |
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Entrez Gene | 58538 |
Alt Symbol | ALS2CR5, DLG6 |
Species | Human |
Gene Type | protein-coding |
Description | membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4) |
Other Description | MAGUK p55 subfamily member 4|amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein|discs large homolog 6|discs, large homolog 6 |
Swissprots | Q96Q44 Q96JB8 Q53TT3 C9IZK4 Q6ZNH6 Q96Q43 |
Accessions | AAY15057 EAW70285 EAW70286 EAW70287 EAW70288 EAW70289 EAW70290 Q96JB8 AB053302 BAB69012 AB053303 BAB69013 AB053304 AF316032 AAK71862 AK131208 BAD18399 AK298589 BAG60779 AK298947 BAG61046 AK300622 BAG62315 BC132785 AAI32786 BC144206 AAI44207 BM999928 BX647162 BX648531 DQ426883 XM_011511571 XP_011509873 XM_011511572 XP_011509874 NM_033066 NP_149055 |
Function | May play a role in retinal photoreceptors development. {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:15914641}. Note=Detected at the outer limiting membrane (OLM) and in the outer plexiform layer (OPL) of the retina. At the OLM, detected apical to the adherens junction (AJ). |
Tissue Specificity | Expressed in the retina (at protein level). Highly expressed in the retina. Lower amounts are detected in brain, testis, ARPE-19, RPE/choroid and fetal eye. Isoform 5 is retina-specific. {ECO:0000269|PubMed:11414766, ECO:0000269|PubMed:12384283, ECO:0000269|PubMed:15558731, ECO:0000269|PubMed:15914641}. |
MISSION® esiRNA - EHU093061 from Sigma-Aldrich
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MISSION® siRNA - SIHK1324 from Sigma-Aldrich
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MISSION® siRNA - SIHK1322 from Sigma-Aldrich
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MISSION® siRNA - SIHK1323 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN14505 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14505 from Sigma-Aldrich
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MPP4 siRNA (Human) - CRJ1753 from Cohesion Biosciences
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MPP4 CRISPR/Cas9 KO Plasmid (h) - sc-412924 from Santa Cruz Biotechnology
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MPP4 HDR Plasmid (h) - sc-412924-HDR from Santa Cruz Biotechnology
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MPP4 Double Nickase Plasmid (h) - sc-412924-NIC from Santa Cruz Biotechnology
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MPP4 Double Nickase Plasmid (h2) - sc-412924-NIC-2 from Santa Cruz Biotechnology
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MPP4 CRISPR Activation Plasmid (h) - sc-412924-ACT from Santa Cruz Biotechnology
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MPP4 CRISPR Activation Plasmid (h2) - sc-412924-ACT-2 from Santa Cruz Biotechnology
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MPP4 Lentiviral Activation Particles (h) - sc-412924-LAC from Santa Cruz Biotechnology
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MPP4 Lentiviral Activation Particles (h2) - sc-412924-LAC-2 from Santa Cruz Biotechnology
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MPP4 siRNA (h) - sc-94843 from Santa Cruz Biotechnology
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MPP4 shRNA Plasmid (h) - sc-94843-SH from Santa Cruz Biotechnology
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MPP4 shRNA (h) Lentiviral Particles - sc-94843-V from Santa Cruz Biotechnology
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MPP4 RNAi - H00058538-R01 from Novus Biologicals
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shRNA set against Human Mpp4 (NM_033066.2) - SHH343956 from Creative biogene
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Human MPP4 siRNA - orb272254 from Biorbyt
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MPP4 shRNA Plasmid (Human) - CHJ1753 from Cohesion Biosciences
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