| Gene Symbol |
CENPJ
|
| Entrez Gene |
55835
|
| Alt Symbol |
BM032, CENP-J, CPAP, LAP, LIP1, MCPH6, SASS4, SCKL4, Sas-4
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
centromere protein J
|
| Other Description |
LAG-3-associated protein|LYST-interacting protein 1|LYST-interacting protein LIP1|LYST-interacting protein LIP7|centrosomal P4.1-associated protein
|
| Swissprots |
Q2KHM6 Q5T6R5 Q9HC77 Q9C067 Q5JPD5 Q96KS5
|
| Accessions |
EAX08351 EAX08352 EAX08353 EAX08354 Q9HC77 AF139625 AAG21074 AF141337 AAG49440 AF141343 AAG49446 AF217509 AAF67620 AJ303006 CAC80028 AK123551 BAG53911 AK292406 BAF85095 AL833182 CAI46195 BC024209 AAH24209 BC062675 BC092467 AAH92467 BC113110 AAI13111 BC113111 AAI13112 BC113662 AAI13663 BC113664 AAI13665 BC143757 BC143758 BU687310 DB029167 DB062002 HQ258541 ADR83295 XM_011535149 XP_011533451 XM_011535150 XP_011533452 XM_011535151 XP_011533453 XR_941627 XR_941628 NM_018451 NP_060921 NR_047594 NR_047595
|
| Function |
Plays an important role in cell division and centrosome function by participating in centriole duplication. Inhibits microtubule nucleation from the centrosome. {ECO:0000269|PubMed:15047868, ECO:0000269|PubMed:17681131, ECO:0000269|PubMed:20531387}.
|
| Subcellular Location |
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Localized within the center of microtubule asters. During centriole biogenesis, it is concentrated within the proximal lumen of both parental centrioles and procentrioles.
|
![Western Blot: CENPJ Overexpression Lysate (Adult Normal) [NBL1-09085] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for CENPJ.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/11990_CENPJ%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBL1-09085-img0002.jpg)