| Gene Symbol |
FGF5
|
| Entrez Gene |
2250
|
| Alt Symbol |
HBGF-5, Smag-82, TCMGLY
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
fibroblast growth factor 5
|
| Other Description |
heparin-binding growth factor 5
|
| Swissprots |
Q3Y8M3 Q8NF90 O75846 P12034 B2R554
|
| Accessions |
AAB60698 AAB60699 AAZ67914 EAX05859 EAX05860 P12034 AA461028 AB016517 BAA33738 AF171928 AAF89742 AF355187 AAQ15127 AF535149 AAN04097 AK090557 BAC03477 AK291962 BAF84651 AK312065 BAG35001 BC074858 AAH74858 BC074859 AAH74859 BC131502 AAI31503 BG252761 BQ001160 DR004226 M37825 AAB06463 NM_001291812 NP_001278741 NM_004464 NP_004455 NM_033143 NP_149134
|
| Function |
Plays an important role in the regulation of cell proliferation and cell differentiation. Required for normal regulation of the hair growth cycle. Functions as an inhibitor of hair elongation by promoting progression from anagen, the growth phase of the hair follicle, into catagen the apoptosis-induced regression phase (By similarity). {ECO:0000250|UniProtKB:Q20FD0}.
|
| Subcellular Location |
Secreted {ECO:0000305}.
|
| Tissue Specificity |
Expressed in neonatal brain.
|
| Top Pathways |
Melanoma, MAPK signaling pathway, PI3K-Akt signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton
|
![Western Blot: FGF5 Overexpression Lysate (Adult Normal) [NBL1-10698] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for FGF5.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/1991_FGF5%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-10698-img0002.jpg)
![Western Blot: FGF5 Overexpression Lysate (Adult Normal) [NBP2-05915] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for FGF5.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/6344_FGF5%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-05915-img0001.jpg)