| Gene Symbol | IFNG |
|---|---|
| Entrez Gene | 3458 |
| Alt Symbol | IFG, IFI |
| Species | Human |
| Gene Type | protein-coding |
| Description | interferon, gamma |
| Other Description | IFN-gamma|immune interferon|interferon gamma |
| Swissprots | Q53ZV4 B5BU88 P01579 |
| Accessions | AAB59534 AAK53058 CAQ43129 EAW97180 P01579 AB451324 BAG70138 AB451453 BAG70267 AF506749 AAM28885 AM903379 CAP17327 AY044154 AAK95388 AY255837 AAP20098 AY255839 AAP20100 BC070256 AAH70256 EF173872 ABM53145 V00543 CAA23804 X01992 CAA26022 X13274 CAA31639 X62468 CAA44325 X62469 CAA44326 X62470 CAA44327 X62471 CAA44328 X62472 CAA44329 X62473 CAA44330 X62474 CAA44331 X87308 NM_000619 NP_000610 |
| Function | Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. |
| Subcellular Location | Secreted. |
| Tissue Specificity | Released primarily from activated T lymphocytes. |
| Top Pathways | Proteasome, Epstein-Barr virus infection, African trypanosomiasis, Herpes simplex infection, Tuberculosis |