| Gene Symbol |
NBL1
|
| Entrez Gene |
4681
|
| Alt Symbol |
D1S1733E, DAN, DAND1, NB, NO3
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
neuroblastoma 1, DAN family BMP antagonist
|
| Other Description |
DAN domain family member 1|differential screening-selected gene aberrant in neuroblastoma|neuroblastoma candidate region, suppression of tumorigenicity 1|neuroblastoma suppressor of tumorigenicity 1
|
| Swissprots |
Q5U0N4 P41271 Q5TGZ2 Q96L68 A3KFI7
|
| Accessions |
BAA92265 EAW94894 EAW94895 P41271 AK292101 BAF84790 AK300872 BAG62517 AK309257 AK313265 BAG36074 AL703187 AY049783 AAL15440 BC012037 AAH12037 BM988954 BQ671197 BT019423 AAV38230 D28124 BAA05671 DA384331 DA921297 DA924824 DA929341 DB016315 DB253522 DB482000 HY084536 NM_001204084 NP_001191013 NM_001204085 NP_001191014 NM_001204086 NP_001191015 NM_001278164 NP_001265093 NM_001278165 NP_001265094 NM_001278166 NP_001265095 NM_005380 NP_005371 NM_182744 NP_877421
|
| Function |
Possible candidate as a tumor suppressor gene of neuroblastoma. May play an important role in preventing cells from entering the final stage (G1/S) of the transformation process.
|
| Subcellular Location |
Secreted.
|
| Tissue Specificity |
Most abundant in normal lung and meningioma.
|
![Western Blot: NBL1 Overexpression Lysate (Adult Normal) [NBL1-13496] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for NBL1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/3117_NBL1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-13496-img0002.jpg)