Gene Symbol | Taf7l |
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Entrez Gene | 74469 |
Alt Symbol | 4933438I11Rik, 50kDa, Taf2q |
Species | Mouse |
Gene Type | protein-coding |
Description | TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor |
Other Description | TATA box binding protein (TBP)-associated factor, RNA polymerase II, Q|TATA box binding protein-associated factor RNA polymerase II subunit Q|TATA box-binding protein-associated factor 50 kDa|transcription initiation factor TFIID 50 kDa subunit|transcription initiation factor TFIID subunit 7-like |
Swissprots | Q9D3R9 Q99MW7 A2AFB9 |
Accessions | EDL20398 Q9D3R9 AF285574 AAK31953 AK017109 BAB30600 AW553087 BB871901 BC106854 AAI06855 XM_006528610 XP_006528673 XM_006528611 XP_006528674 XM_006528613 XP_006528676 XM_006528614 XP_006528677 XM_006528615 XP_006528678 NM_028958 NP_083234 |
Function | Probably functions as a spermatogensis-specific component of the DNA-binding general transcription factor complex TFIID, a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. May play a role in spermatogenesis. {ECO:0000269|PubMed:12665565}. |
Subcellular Location | Nucleus. Cytoplasm. Note=Cytoplasmic in spermatogonia and early spermatocytes (preleptotene, leptotene, and zygotene); translocates into the nuclei of pachytene spermatocytes and round spermatids. |
Tissue Specificity | Testis-specific (at protein level). Expressed during spermatogenesis from spermatogonia stage up to the stage of round spermatids. {ECO:0000269|PubMed:11279525, ECO:0000269|PubMed:17242199}. |
Top Pathways | Basal transcription factors |
TAF7L CRISPR/Cas9 KO Plasmid (m) - sc-428899 from Santa Cruz Biotechnology
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TAF7L HDR Plasmid (m) - sc-428899-HDR from Santa Cruz Biotechnology
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TAF7L Double Nickase Plasmid (m) - sc-428899-NIC from Santa Cruz Biotechnology
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TAF7L Double Nickase Plasmid (m2) - sc-428899-NIC-2 from Santa Cruz Biotechnology
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TAF7L CRISPR Activation Plasmid (m) - sc-428899-ACT from Santa Cruz Biotechnology
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TAF7L CRISPR Activation Plasmid (m2) - sc-428899-ACT-2 from Santa Cruz Biotechnology
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TAF7L Lentiviral Activation Particles (m) - sc-428899-LAC from Santa Cruz Biotechnology
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TAF7L Lentiviral Activation Particles (m2) - sc-428899-LAC-2 from Santa Cruz Biotechnology
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TAF7L siRNA (m) - sc-154054 from Santa Cruz Biotechnology
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TAF7L shRNA Plasmid (m) - sc-154054-SH from Santa Cruz Biotechnology
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TAF7L shRNA (m) Lentiviral Particles - sc-154054-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU089961 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN42457 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND42457 from Sigma-Aldrich
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TAF7L siRNA (Mouse) - CRM9265 from Cohesion Biosciences
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TAF7L - MBS8210515 from MyBioSource
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shRNA set against Mouse TAF7L (NM_028958.4) - SHH422806 from Creative biogene
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Mouse TAF7L siRNA - orb288741 from Biorbyt
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TAF7L shRNA Plasmid (Mouse) - CHM9265 from Cohesion Biosciences
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