Gene Symbol | NDUFV2 |
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Entrez Gene | 4729 |
Alt Symbol | CI-24k |
Species | Human |
Gene Type | protein-coding |
Description | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa |
Other Description | NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial|NADH dehydrogenase ubiquinone flavoprotein 2, mitochondrial|NADH-ubiquinone oxidoreductase 24 kDa subunit|NADH-ubiquinone oxidoreductase flavoprotein 2|complex I 24kDa subunit|complex I, mitochondrial respitory chain, 24 kD subunit|nuclear-encoded mitochondrial NADH-ubiquinone reductase 24Kd subunit |
Swissprots | Q9BV41 P19404 |
Accessions | BAA11028 BAA25988 EAX01612 P19404 AF147367 AK291865 BAF84554 AK312129 BAG35065 AW051350 BC001632 AAH01632 BC017487 AAH17487 BC071689 AAH71689 BG742948 CB121843 CR456928 CAG33209 DQ892593 ABM83519 DQ895813 ABM86739 M22538 AAA75390 XR_243808 NM_021074 NP_066552 |
Function | Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). {ECO:0000250}. |
Subcellular Location | Mitochondrion inner membrane. |
Top Pathways | Alzheimer's disease, Huntington's disease, Non-alcoholic fatty liver disease (NAFLD), Oxidative phosphorylation |
NDUFV2 CRISPR/Cas9 KO Plasmid (h) - sc-403777 from Santa Cruz Biotechnology
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NDUFV2 HDR Plasmid (h) - sc-403777-HDR from Santa Cruz Biotechnology
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NDUFV2 Double Nickase Plasmid (h) - sc-403777-NIC from Santa Cruz Biotechnology
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NDUFV2 Double Nickase Plasmid (h2) - sc-403777-NIC-2 from Santa Cruz Biotechnology
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NDUFV2 CRISPR Activation Plasmid (h) - sc-403777-ACT from Santa Cruz Biotechnology
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NDUFV2 CRISPR Activation Plasmid (h2) - sc-403777-ACT-2 from Santa Cruz Biotechnology
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NDUFV2 Lentiviral Activation Particles (h) - sc-403777-LAC from Santa Cruz Biotechnology
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NDUFV2 Lentiviral Activation Particles (h2) - sc-403777-LAC-2 from Santa Cruz Biotechnology
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NDUFV2 siRNA (h) - sc-106292 from Santa Cruz Biotechnology
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NDUFV2 shRNA Plasmid (h) - sc-106292-SH from Santa Cruz Biotechnology
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NDUFV2 shRNA (h) Lentiviral Particles - sc-106292-V from Santa Cruz Biotechnology
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NDUFV2 RNAi - H00004729-R01 from Novus Biologicals
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MISSION® esiRNA - EHU107761 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN15175 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15175 from Sigma-Aldrich
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NDUFV2 siRNA (Human) - CRH3141 from Cohesion Biosciences
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Human NDUFV2 siRNA - orb263643 from Biorbyt
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NDUFV2 shRNA Plasmid (Human) - CHH3141 from Cohesion Biosciences
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