Gene Symbol | MAMLD1 |
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Entrez Gene | 10046 |
Alt Symbol | CG1, CXorf6, F18, HYSP2 |
Species | Human |
Gene Type | protein-coding |
Description | mastermind-like domain containing 1 |
Other Description | mastermind-like domain-containing protein 1 |
Swissprots | B4DG93 B2RCQ4 Q13495 B9EGA5 |
Accessions | EAW99376 Q13495 AK094563 AK125184 BAC86075 AK294478 BAG57704 AK297504 BAG59917 AK302612 BAG63859 AK315217 BAG37651 AW594465 BC136324 AAI36325 BU687638 BX537560 DA106253 DA527328 DC320452 DR001800 U46023 AAC50551 XM_006724802 XP_006724865 XM_006724803 XP_006724866 XM_011531092 XP_011529394 XM_011531093 XP_011529395 XM_011531094 XP_011529396 XM_011531095 XP_011529397 XM_011531096 XP_011529398 NM_001177465 NP_001170936 NM_001177466 NP_001170937 NM_005491 NP_005482 |
Function | Transactivates the HES3 promoter independently of NOTCH proteins. HES3 is a non-canonical NOTCH target gene which lacks binding sites for RBPJ. {ECO:0000269|PubMed:18162467}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:18162467}. Note=Punctate nuclear localization. |
Tissue Specificity | Expressed in fetal brain, fetal ovary and fetal testis. Expressed in adult brain, ovary, skin, testis, uterus. Highly expressed in skeletal muscle. {ECO:0000269|PubMed:18162467}. |
MAMLD1 CRISPR/Cas9 KO Plasmid (h) - sc-411409 from Santa Cruz Biotechnology
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MAMLD1 HDR Plasmid (h) - sc-411409-HDR from Santa Cruz Biotechnology
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CXorf6 Double Nickase Plasmid (h) - sc-411409-NIC from Santa Cruz Biotechnology
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MAMLD1 Double Nickase Plasmid (h2) - sc-411409-NIC-2 from Santa Cruz Biotechnology
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CXorf6 CRISPR Activation Plasmid (h) - sc-411409-ACT from Santa Cruz Biotechnology
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MAMLD1 CRISPR Activation Plasmid (h2) - sc-411409-ACT-2 from Santa Cruz Biotechnology
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CXorf6 Lentiviral Activation Particles (h) - sc-411409-LAC from Santa Cruz Biotechnology
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MAMLD1 Lentiviral Activation Particles (h2) - sc-411409-LAC-2 from Santa Cruz Biotechnology
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MAMLD1 siRNA (h) - sc-91240 from Santa Cruz Biotechnology
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MAMLD1 shRNA Plasmid (h) - sc-91240-SH from Santa Cruz Biotechnology
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MAMLD1 shRNA (h) Lentiviral Particles - sc-91240-V from Santa Cruz Biotechnology
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MAMLD1 RNAi - H00010046-R01 from Novus Biologicals
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MISSION® esiRNA - EHU035871 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN12959 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND12959 from Sigma-Aldrich
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MAMLD1 siRNA (Human) - CRH6762 from Cohesion Biosciences
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shRNA set against Human MAMLD1 (NM_005491.3) - SHH337223 from Creative biogene
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MAMLD1 shRNA Plasmid (Human) - CHH6762 from Cohesion Biosciences
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MAMLD1 miRNA 3'UTR clone - MiUTR4H-TG05314 from Creative biogene
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