Gene Symbol | GSTM1 |
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Entrez Gene | 2944 |
Alt Symbol | GST1, GSTM1-1, GSTM1a-1a, GSTM1b-1b, GTH4, GTM1, H-B, MU, MU-1 |
Species | Human |
Gene Type | protein-coding |
Description | glutathione S-transferase mu 1 |
Other Description | GST HB subunit 4|GST class-mu 1|HB subunit 4|S-(hydroxyalkyl)glutathione lyase|glutathione S-alkyltransferase|glutathione S-aralkyltransferase|glutathione S-aryltransferase|glutathione S-transferase M1|glutathione S-transferase Mu 1 |
Swissprots | Q8TC98 Q9UC96 Q5GHG0 Q6FH88 P09488 |
Accessions | AAD13938 CAA35817 CAA48636 P09488 AY510272 AAR85979 AY532926 AAT06767 AY532927 AAT06768 BC024005 AAH24005 BC036805 BC095463 BQ436476 CR541868 CAG46666 DB459176 GQ129273 ACT64407 GQ129274 ACT64408 HQ448375 ADQ32855 J03817 AAA59203 KJ534856 AHW56496 KJ534857 AHW56497 KJ534858 AHW56498 KJ534998 AHW56638 KJ535021 AHW56660 X08020 CAA30821 XM_005270782 XP_005270839 XM_005270783 XP_005270840 NM_000561 NP_000552 NM_146421 NP_666533 |
Function | Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. {ECO:0000269|PubMed:16548513}. |
Subcellular Location | Cytoplasm. |
Tissue Specificity | Liver (at protein level). {ECO:0000269|PubMed:7822249}. |
Top Pathways | Chemical carcinogenesis, Glutathione metabolism, Metabolism of xenobiotics by cytochrome P450, Drug metabolism - cytochrome P450 |
GSTM1 CRISPR/Cas9 KO Plasmid (h) - sc-418201 from Santa Cruz Biotechnology
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GSTM1 HDR Plasmid (h) - sc-418201-HDR from Santa Cruz Biotechnology
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GSTM1 Double Nickase Plasmid (h) - sc-418201-NIC from Santa Cruz Biotechnology
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GSTM1 Double Nickase Plasmid (h2) - sc-418201-NIC-2 from Santa Cruz Biotechnology
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GSTM1 CRISPR Activation Plasmid (h) - sc-418201-ACT from Santa Cruz Biotechnology
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GSTM1 CRISPR Activation Plasmid (h2) - sc-418201-ACT-2 from Santa Cruz Biotechnology
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GSTM1 Lentiviral Activation Particles (h) - sc-418201-LAC from Santa Cruz Biotechnology
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GSTM1 Lentiviral Activation Particles (h2) - sc-418201-LAC-2 from Santa Cruz Biotechnology
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GSTM1 siRNA (h) - sc-44461 from Santa Cruz Biotechnology
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GSTM1 shRNA Plasmid (h) - sc-44461-SH from Santa Cruz Biotechnology
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GSTM1 shRNA (h) Lentiviral Particles - sc-44461-V from Santa Cruz Biotechnology
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Glutathione S-Transferase mu 1/GSTM1 RNAi - H00002944-R02 from Novus Biologicals
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MISSION® esiRNA - EHU115801 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN1747 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1747 from Sigma-Aldrich
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GSTM1 siRNA (Human) - CRH1990 from Cohesion Biosciences
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Glutathione S-Transferase mu 1/GSTM1 RNAi - H00002944-R01 from Novus Biologicals
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GSTM1 - MBS8225623 from MyBioSource
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GSTM1 CRISPR/Cas9 KO Plasmid (h2) - sc-418201-KO-2 from Santa Cruz Biotechnology
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GSTM1 HDR Plasmid (h2) - sc-418201-HDR-2 from Santa Cruz Biotechnology
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Human GSTM1 siRNA - orb262492 from Biorbyt
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GSTM1 shRNA Plasmid (Human) - CHH1990 from Cohesion Biosciences
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GSTM1 miRNA 3'UTR clone - MiUTR3H-00911 from Creative biogene
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GSTM1 miRNA 3'UTR clone - MiUTR3H-00912 from Creative biogene
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