Gene Symbol | TOM1L1 |
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Entrez Gene | 10040 |
Alt Symbol | OK/KNS-CL.3, SRCASM |
Species | Human |
Gene Type | protein-coding |
Description | target of myb1 (chicken)-like 1 |
Other Description | Src activating and signaling molecule|TOM1-like protein 1|src-activating and signaling molecule protein|target of Myb-like protein 1|target of myb 1-like 1|target of myb1-like 1 |
Swissprots | Q53G06 Q8N749 B7Z9E2 O75674 |
Accessions | EAW94551 EAW94552 EAW94553 O75674 AB065085 BAB93522 AJ010071 CAA08993 AK001893 AK223125 BAD96845 AK225351 AK300823 BAG62477 AK303912 BAG64841 AK303913 BAG64842 AK309164 AK315039 BAG37522 AK315907 BAH14278 AW044673 AW139144 BC029396 AAH29396 CN284148 XM_011524153 XP_011522455 XM_011524154 XP_011522456 XM_011524155 XP_011522457 XM_011524156 XP_011522458 XR_243612 XR_934340 NM_005486 NP_005477 |
Function | Probable adapter protein involved in signaling pathways. Interacts with the SH2 and SH3 domains of various signaling proteins when it is phosphorylated. May promote FYN activation, possibly by disrupting intramolecular SH3-dependent interactions (By similarity). {ECO:0000250}. |
Subcellular Location | Golgi apparatus, Golgi stack. Endosome membrane {ECO:0000305}. Cytoplasm {ECO:0000250}. Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=A small proportion is membrane-associated. {ECO:0000250}. |
Tom1L-1 CRISPR/Cas9 KO Plasmid (h) - sc-408034 from Santa Cruz Biotechnology
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Tom1L-1 HDR Plasmid (h) - sc-408034-HDR from Santa Cruz Biotechnology
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Tom1L-1 Double Nickase Plasmid (h) - sc-408034-NIC from Santa Cruz Biotechnology
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Tom1L-1 Double Nickase Plasmid (h2) - sc-408034-NIC-2 from Santa Cruz Biotechnology
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Tom1L-1 CRISPR Activation Plasmid (h) - sc-408034-ACT from Santa Cruz Biotechnology
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Tom1L-1 CRISPR Activation Plasmid (h2) - sc-408034-ACT-2 from Santa Cruz Biotechnology
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Tom1L-1 Lentiviral Activation Particles (h) - sc-408034-LAC from Santa Cruz Biotechnology
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Tom1L-1 Lentiviral Activation Particles (h2) - sc-408034-LAC-2 from Santa Cruz Biotechnology
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Tom1L-1 siRNA (h) - sc-76708 from Santa Cruz Biotechnology
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Tom1L-1 shRNA Plasmid (h) - sc-76708-SH from Santa Cruz Biotechnology
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Tom1L-1 shRNA (h) Lentiviral Particles - sc-76708-V from Santa Cruz Biotechnology
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TOM1L1 RNAi - H00010040-R01 from Novus Biologicals
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MISSION® esiRNA - EHU111521 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN21810 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21810 from Sigma-Aldrich
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TOM1L1 siRNA (Human) - CRH6757 from Cohesion Biosciences
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TOM1L1 - MBS8201326 from MyBioSource
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Human TOM1L1 siRNA - orb267259 from Biorbyt
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TOM1L1 shRNA Plasmid (Human) - CHH6757 from Cohesion Biosciences
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TOM1L1 miRNA 3'UTR clone - MiUTR3H-07023 from Creative biogene
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