Gene Symbol | MTIF3 |
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Entrez Gene | 219402 |
Alt Symbol | IF3mt |
Species | Human |
Gene Type | protein-coding |
Description | mitochondrial translational initiation factor 3 |
Other Description | IF-3(Mt)|translation initiation factor IF-3, mitochondrial |
Swissprots | Q86X68 Q5W0V0 Q05BL8 Q9H2K0 |
Accessions | EAX08406 EAX08407 EAX08408 EAX08409 EAX08410 EAX08411 EAX08412 Q9H2K0 AF410851 AAL04150 AK090995 AK094420 BC039599 AAH39599 BC046166 AAH46166 BG617536 BI460170 BM312841 BM548061 BM768315 CN272769 DB456678 DB470026 HQ448635 ADQ33113 XM_005266283 XP_005266340 XM_006719771 XP_006719834 XM_006719772 XP_006719835 XM_011534957 XP_011533259 XM_011534958 XP_011533260 XM_011534959 XP_011533261 XM_011534960 XP_011533262 XM_011534961 XP_011533263 XM_011534962 XP_011533264 XM_011534963 XP_011533265 NM_001166261 NP_001159733 NM_001166262 NP_001159734 NM_001166263 NP_001159735 NM_152912 NP_690876 |
Function | IF-3 binds to the 28S ribosomal subunit and shifts the equilibrum between 55S ribosomes and their 39S and 28S subunits in favor of the free subunits, thus enhancing the availability of 28S subunits on which protein synthesis initiation begins. {ECO:0000269|PubMed:12095986}. |
Subcellular Location | Mitochondrion {ECO:0000305}. |
IF3 CRISPR/Cas9 KO Plasmid (h) - sc-415050 from Santa Cruz Biotechnology
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IF3 HDR Plasmid (h) - sc-415050-HDR from Santa Cruz Biotechnology
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IF3 Double Nickase Plasmid (h) - sc-415050-NIC from Santa Cruz Biotechnology
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IF3 Double Nickase Plasmid (h2) - sc-415050-NIC-2 from Santa Cruz Biotechnology
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IF3 CRISPR Activation Plasmid (h) - sc-415050-ACT from Santa Cruz Biotechnology
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IF3 CRISPR Activation Plasmid (h2) - sc-415050-ACT-2 from Santa Cruz Biotechnology
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IF3 Lentiviral Activation Particles (h) - sc-415050-LAC from Santa Cruz Biotechnology
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IF3 Lentiviral Activation Particles (h2) - sc-415050-LAC-2 from Santa Cruz Biotechnology
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IF3 siRNA (h) - sc-75319 from Santa Cruz Biotechnology
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IF3 shRNA Plasmid (h) - sc-75319-SH from Santa Cruz Biotechnology
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IF3 shRNA (h) Lentiviral Particles - sc-75319-V from Santa Cruz Biotechnology
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Mitocondrial Translational Initiation Factor 3 RNAi - H00219402-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN14711 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14711 from Sigma-Aldrich
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MTIF3 siRNA (Human) - CRJ6372 from Cohesion Biosciences
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shRNA set against Human MTIF3 (NM_152912.4) - SHH346396 from Creative biogene
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Human MTIF3 siRNA - orb276873 from Biorbyt
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MTIF3 shRNA Plasmid (Human) - CHJ6372 from Cohesion Biosciences
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MTIF3 miRNA 3'UTR clone - MiUTR4H-TG05711 from Creative biogene
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