Gene Symbol | UCP2 |
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Entrez Gene | 7351 |
Alt Symbol | BMIQ4, SLC25A8, UCPH |
Species | Human |
Gene Type | protein-coding |
Description | uncoupling protein 2 (mitochondrial, proton carrier) |
Other Description | mitochondrial uncoupling protein 2|solute carrier family 25 member 8 |
Swissprots | Q4PJH8 P55851 Q53HM3 |
Accessions | AAC39690 AAD21151 AAY68217 CAA11402 EAW74923 EAW74924 P55851 AK025742 AK222540 BAD96260 AK222557 BAD96277 BC011737 AAH11737 DQ893298 ABM84224 DQ896736 ABM87735 U76367 AAB48411 U82819 AAC51336 U94592 AAB53091 NM_003355 NP_003346 |
Function | UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat. |
Subcellular Location | Mitochondrion inner membrane; Multi-pass membrane protein. |
Tissue Specificity | Widely expressed in adult human tissues, including tissues rich in macrophages. Most expressed in white adipose tissue and skeletal muscle. |
UCP2 CRISPR/Cas9 KO Plasmid (h) - sc-400319 from Santa Cruz Biotechnology
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UCP2 HDR Plasmid (h) - sc-400319-HDR from Santa Cruz Biotechnology
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UCP2 Double Nickase Plasmid (h) - sc-400319-NIC from Santa Cruz Biotechnology
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UCP2 Double Nickase Plasmid (h2) - sc-400319-NIC-2 from Santa Cruz Biotechnology
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UCP2 CRISPR Activation Plasmid (h) - sc-400319-ACT from Santa Cruz Biotechnology
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UCP2 CRISPR Activation Plasmid (h2) - sc-400319-ACT-2 from Santa Cruz Biotechnology
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UCP2 Lentiviral Activation Particles (h) - sc-400319-LAC from Santa Cruz Biotechnology
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UCP2 Lentiviral Activation Particles (h2) - sc-400319-LAC-2 from Santa Cruz Biotechnology
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UCP2 siRNA (h) - sc-42682 from Santa Cruz Biotechnology
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UCP2 shRNA Plasmid (h) - sc-42682-SH from Santa Cruz Biotechnology
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UCP2 shRNA (h) Lentiviral Particles - sc-42682-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU007971 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2153 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2153 from Sigma-Aldrich
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UCP2 siRNA (Human) - CRH5026 from Cohesion Biosciences
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UCP2 RNAi - H00007351-R01 from Novus Biologicals
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UCP2 - MBS8228462 from MyBioSource
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shRNA set against Human Ucp2 (NM_003355.2) - SHH439884 from Creative biogene
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shRNA set against Human UCP2(NM_003355.2) - SHL104758 from Creative biogene
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UCP2 shRNA Plasmid (Human) - CHH5026 from Cohesion Biosciences
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UCP2 miRNA 3'UTR clone - MiUTR1H-10981 from Creative biogene
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