Gene Symbol | PNPLA3 |
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Entrez Gene | 80339 |
Alt Symbol | ADPN, C22orf20, iPLA(2)epsilon |
Species | Human |
Gene Type | protein-coding |
Description | patatin-like phospholipase domain containing 3 |
Other Description | acylglycerol O-acyltransferase|adiponutrin|calcium-independent phospholipase A2-epsilon|iPLA2-epsilon|iPLA2epsilon|patatin-like phospholipase domain-containing protein 3 |
Swissprots | Q9NST1 B3KW00 B2RCL3 Q6P1A1 B0QYI0 Q96CB4 |
Accessions | AGW25376 AGW25377 EAW73323 EAW73324 EAW73325 Q9NST1 AK025665 AK123806 BAG53962 AK315166 BAG37610 AL138578 CAB71238 BC014449 AAH14449 BC065195 AAH65195 CR456476 CAG30362 NM_025225 NP_079501 |
Function | Multifunctional enzyme which has both triacylglycerol lipase and acylglycerol O-acyltransferase activities. {ECO:0000269|PubMed:15364929}. |
Subcellular Location | Membrane {ECO:0000269|PubMed:15364929}; Single-pass type II membrane protein {ECO:0000269|PubMed:15364929}. |
Top Pathways | Glycerolipid metabolism |
ADPN CRISPR/Cas9 KO Plasmid (h) - sc-406096 from Santa Cruz Biotechnology
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ADPN HDR Plasmid (h) - sc-406096-HDR from Santa Cruz Biotechnology
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ADPN Double Nickase Plasmid (h) - sc-406096-NIC from Santa Cruz Biotechnology
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ADPN Double Nickase Plasmid (h2) - sc-406096-NIC-2 from Santa Cruz Biotechnology
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ADPN CRISPR Activation Plasmid (h) - sc-406096-ACT from Santa Cruz Biotechnology
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ADPN CRISPR Activation Plasmid (h2) - sc-406096-ACT-2 from Santa Cruz Biotechnology
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ADPN Lentiviral Activation Particles (h) - sc-406096-LAC from Santa Cruz Biotechnology
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ADPN Lentiviral Activation Particles (h2) - sc-406096-LAC-2 from Santa Cruz Biotechnology
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ADPN siRNA (h) - sc-60129 from Santa Cruz Biotechnology
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ADPN shRNA Plasmid (h) - sc-60129-SH from Santa Cruz Biotechnology
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ADPN shRNA (h) Lentiviral Particles - sc-60129-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU054621 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17064 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17064 from Sigma-Aldrich
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PNPLA3 siRNA (Human) - CRJ2866 from Cohesion Biosciences
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shRNA set against Human PNPLA3 (NM_025225.2) - SHH378800 from Creative biogene
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shRNA set against Human PNPLA3(NM_025225.2) - SHR125286 from Creative biogene
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Human PNPLA3 siRNA - orb273367 from Biorbyt
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PNPLA3 shRNA Plasmid (Human) - CHJ2866 from Cohesion Biosciences
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PNPLA3 miRNA 3'UTR clone - MiUTR1H-08051 from Creative biogene
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