Gene Symbol | SEMA6C |
---|---|
Entrez Gene | 10500 |
Alt Symbol | SEMAY, m-SemaY, m-SemaY2 |
Species | Human |
Gene Type | protein-coding |
Description | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C |
Other Description | sema Y|semaphorin-6C|semaphorin-Y |
Swissprots | D3DV15 Q8WXT8 Q5JR73 Q8WXT9 Q96JF8 Q5JR72 Q5JR71 Q8WXU0 Q9H3T2 |
Accessions | EAW53469 EAW53470 EAW53471 EAW53472 Q9H3T2 AB022434 BAB20670 AB058772 BAB47498 AF055020 AAC09365 AF339152 AAL72098 AF339153 AAL72099 AF339154 AAL72100 AK302862 BAG64046 AK311613 AL122064 CAB59243 AU279414 BC114521 AAI14522 BC114623 AAI14624 BE253393 DA787858 XM_005244835 XP_005244892 XM_011509075 XP_011507377 NM_001178061 NP_001171532 NM_001178062 NP_001171533 NM_030913 NP_112175 |
Function | Shows growth cone collapsing activity on dorsal root ganglion (DRG) neurons in vitro. May be a stop signal for the DRG neurons in their target areas, and possibly also for other neurons. May also be involved in the maintenance and remodeling of neuronal connections. {ECO:0000269|PubMed:12110693}. |
Subcellular Location | Cell membrane; Single-pass type I membrane protein. |
Tissue Specificity | In adult tissues, expressed only in skeletal muscle. {ECO:0000269|PubMed:12110693}. |
Top Pathways | Axon guidance |
SEMA6C CRISPR/Cas9 KO Plasmid (h) - sc-418281 from Santa Cruz Biotechnology
|
||||||||
SEMA6C HDR Plasmid (h) - sc-418281-HDR from Santa Cruz Biotechnology
|
||||||||
SEMA6C Double Nickase Plasmid (h) - sc-418281-NIC from Santa Cruz Biotechnology
|
||||||||
SEMA6C Double Nickase Plasmid (h2) - sc-418281-NIC-2 from Santa Cruz Biotechnology
|
||||||||
SEMA6C CRISPR Activation Plasmid (h) - sc-418281-ACT from Santa Cruz Biotechnology
|
||||||||
SEMA6C CRISPR Activation Plasmid (h2) - sc-418281-ACT-2 from Santa Cruz Biotechnology
|
||||||||
SEMA6C Lentiviral Activation Particles (h) - sc-418281-LAC from Santa Cruz Biotechnology
|
||||||||
SEMA6C Lentiviral Activation Particles (h2) - sc-418281-LAC-2 from Santa Cruz Biotechnology
|
||||||||
SEMA6C siRNA (h) - sc-76472 from Santa Cruz Biotechnology
|
||||||||
SEMA6C shRNA Plasmid (h) - sc-76472-SH from Santa Cruz Biotechnology
|
||||||||
SEMA6C shRNA (h) Lentiviral Particles - sc-76472-V from Santa Cruz Biotechnology
|
||||||||
Semaphorin 6C RNAi - H00010500-R02 from Novus Biologicals
|
||||||||
MISSION® esiRNA - EHU152141 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN19080 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19080 from Sigma-Aldrich
|
||||||||
MISSION® 3′UTR Lenti GoClone™ - HUTR07108 from Sigma-Aldrich
|
||||||||
SEMA6C siRNA (Human) - CRH7136 from Cohesion Biosciences
|
||||||||
SEMA6C - MBS8208946 from MyBioSource
|
||||||||
Human SEMA6C siRNA - orb267638 from Biorbyt
|
||||||||
SEMA6C shRNA Plasmid (Human) - CHH7136 from Cohesion Biosciences
|