Gene Symbol | GRXCR1 |
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Entrez Gene | 389207 |
Alt Symbol | DFNB25, PPP1R88 |
Species | Human |
Gene Type | protein-coding |
Description | glutaredoxin, cysteine rich 1 |
Other Description | glutaredoxin domain-containing cysteine-rich protein 1|protein phosphatase 1, regulatory subunit 88 |
Swissprots | A8MXD5 |
Accessions | A8MXD5 AA588868 BC148672 AAI48673 BC153209 AAI53210 BG213384 DT932651 DY654338 XM_011513691 XP_011511993 NM_001080476 NP_001073945 |
Function | May play a role in actin filament architecture in developing stereocilia of sensory cells. {ECO:0000250}. |
Subcellular Location | Cell projection, stereocilium {ECO:0000250}. Cell projection, microvillus {ECO:0000250}. Cell projection, kinocilium {ECO:0000250}. Note=In the inner ear, localized to stereocilia, apical microvilli of sensory cells and kinocilia. {ECO:0000250}. |
Tissue Specificity | Expressed at low levels in adult lung, brain and duodenum with moderate levels in testis. Highly expressed in fetal cochlea. {ECO:0000269|PubMed:20137778}. |
GRXCR1 CRISPR/Cas9 KO Plasmid (h) - sc-409109 from Santa Cruz Biotechnology
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GRXCR1 HDR Plasmid (h) - sc-409109-HDR from Santa Cruz Biotechnology
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GRXCR1 Double Nickase Plasmid (h) - sc-409109-NIC from Santa Cruz Biotechnology
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GRXCR1 Double Nickase Plasmid (h2) - sc-409109-NIC-2 from Santa Cruz Biotechnology
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GRXCR1 CRISPR Activation Plasmid (h) - sc-409109-ACT from Santa Cruz Biotechnology
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GRXCR1 CRISPR Activation Plasmid (h2) - sc-409109-ACT-2 from Santa Cruz Biotechnology
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GRXCR1 Lentiviral Activation Particles (h) - sc-409109-LAC from Santa Cruz Biotechnology
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GRXCR1 Lentiviral Activation Particles (h2) - sc-409109-LAC-2 from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU146701 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9715 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9715 from Sigma-Aldrich
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GRXCR1 siRNA (Human) - CRJ7869 from Cohesion Biosciences
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GRXCR1 - MBS8239430 from MyBioSource
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shRNA set against Human GRXCR1 (NM_001080476.2) - SHH308298 from Creative biogene
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GRXCR1 shRNA Plasmid (Human) - CHJ7869 from Cohesion Biosciences
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GRXCR1 miRNA 3'UTR clone - MiUTR4H-TG11377 from Creative biogene
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