Gene Symbol |
JAG2
|
Entrez Gene |
3714
|
Alt Symbol |
HJ2, SER2
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
jagged 2
|
Other Description |
protein jagged-2
|
Swissprots |
Q9UE99 Q9Y6P9 Q9Y219 Q9Y6Q0 Q9UNK8 Q9UE17
|
Accessions |
AAD15562 EAW81899 EAW81900 EAW81901 Q9Y219 AA775404 AB209370 BAD92607 AF003521 AAB61285 AF020201 AAB71189 AF029778 AAB84215 AF029779 AAB84216 AI276672 AJ712299 BC032053 BX105691 LN607838 CEF49525 U69180 Y14330 CAA74706 XM_011536736 XP_011535038 NM_002226 NP_002217 NM_145159 NP_660142
|
Function |
Putative Notch ligand involved in the mediation of Notch signaling. Involved in limb development (By similarity). {ECO:0000250}.
|
Subcellular Location |
Membrane; Single-pass type I membrane protein.
|
Tissue Specificity |
Expressed in heart, placenta and skeletal muscle and to a lesser extend in pancreas. Very low expression in brain, lung, liver and kidney.
|
Top Pathways |
Notch signaling pathway
|