JAG2

Gene Symbol JAG2
Entrez Gene 3714
Alt Symbol HJ2, SER2
Species Human
Gene Type protein-coding
Description jagged 2
Other Description protein jagged-2
Swissprots Q9UE99 Q9Y6P9 Q9Y219 Q9Y6Q0 Q9UNK8 Q9UE17
Accessions AAD15562 EAW81899 EAW81900 EAW81901 Q9Y219 AA775404 AB209370 BAD92607 AF003521 AAB61285 AF020201 AAB71189 AF029778 AAB84215 AF029779 AAB84216 AI276672 AJ712299 BC032053 BX105691 LN607838 CEF49525 U69180 Y14330 CAA74706 XM_011536736 XP_011535038 NM_002226 NP_002217 NM_145159 NP_660142
Function Putative Notch ligand involved in the mediation of Notch signaling. Involved in limb development (By similarity). {ECO:0000250}.
Subcellular Location Membrane; Single-pass type I membrane protein.
Tissue Specificity Expressed in heart, placenta and skeletal muscle and to a lesser extend in pancreas. Very low expression in brain, lung, liver and kidney.
Top Pathways Notch signaling pathway