Gene Symbol | JAG2 |
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Entrez Gene | 3714 |
Alt Symbol | HJ2, SER2 |
Species | Human |
Gene Type | protein-coding |
Description | jagged 2 |
Other Description | protein jagged-2 |
Swissprots | Q9UE99 Q9Y6P9 Q9Y219 Q9Y6Q0 Q9UNK8 Q9UE17 |
Accessions | AAD15562 EAW81899 EAW81900 EAW81901 Q9Y219 AA775404 AB209370 BAD92607 AF003521 AAB61285 AF020201 AAB71189 AF029778 AAB84215 AF029779 AAB84216 AI276672 AJ712299 BC032053 BX105691 LN607838 CEF49525 U69180 Y14330 CAA74706 XM_011536736 XP_011535038 NM_002226 NP_002217 NM_145159 NP_660142 |
Function | Putative Notch ligand involved in the mediation of Notch signaling. Involved in limb development (By similarity). {ECO:0000250}. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Tissue Specificity | Expressed in heart, placenta and skeletal muscle and to a lesser extend in pancreas. Very low expression in brain, lung, liver and kidney. |
Top Pathways | Notch signaling pathway |
Jagged2 CRISPR/Cas9 KO Plasmid (h) - sc-401322 from Santa Cruz Biotechnology
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Jagged2 HDR Plasmid (h) - sc-401322-HDR from Santa Cruz Biotechnology
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Jagged2 Double Nickase Plasmid (h) - sc-401322-NIC from Santa Cruz Biotechnology
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Jagged2 Double Nickase Plasmid (h2) - sc-401322-NIC-2 from Santa Cruz Biotechnology
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Jagged2 CRISPR Activation Plasmid (h) - sc-401322-ACT from Santa Cruz Biotechnology
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Jagged2 CRISPR Activation Plasmid (h2) - sc-401322-ACT-2 from Santa Cruz Biotechnology
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Jagged2 Lentiviral Activation Particles (h) - sc-401322-LAC from Santa Cruz Biotechnology
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Jagged2 Lentiviral Activation Particles (h2) - sc-401322-LAC-2 from Santa Cruz Biotechnology
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Jagged2 siRNA (h) - sc-39672 from Santa Cruz Biotechnology
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Jagged2 shRNA Plasmid (h) - sc-39672-SH from Santa Cruz Biotechnology
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Jagged2 shRNA (h) Lentiviral Particles - sc-39672-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU158101 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10853 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10853 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07614 from Sigma-Aldrich
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JAG2 siRNA (Human) - CRH2501 from Cohesion Biosciences
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Jagged 2 RNAi - H00003714-R02 from Novus Biologicals
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Jagged 2 RNAi - H00003714-R01 from Novus Biologicals
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JAG2, siRNA - MBS8236406 from MyBioSource
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shRNA set against Human JAG2 (NM_002226.4) - SHH321887 from Creative biogene
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Human JAG2 siRNA - orb263003 from Biorbyt
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JAG2 shRNA Plasmid (Human) - CHH2501 from Cohesion Biosciences
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JAG2 miRNA 3'UTR clone - MiUTR3H-05088 from Creative biogene
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JAG2 miRNA 3'UTR clone - MiUTR3H-05089 from Creative biogene
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