| Gene Symbol | FXYD2 |
|---|---|
| Entrez Gene | 486 |
| Alt Symbol | ATP1G1, HOMG2 |
| Species | Human |
| Gene Type | protein-coding |
| Description | FXYD domain containing ion transport regulator 2 |
| Other Description | ATPase, Na+/K+ transporting, gamma 1 polypeptide|Na(+)/K(+) ATPase subunit gamma|sodium pump gamma chain|sodium/potassium-transporting ATPase subunit gamma |
| Swissprots | Q9GZQ7 P54710 Q15332 Q9GZP3 Q53YC1 |
| Accessions | AAG34359 AAG34360 AAG37906 AAG37907 EAW67325 EAW67326 P54710 AA309757 AA814197 AF241236 AAG34361 AK096069 BAC04693 BC005302 AAH05302 BC013289 AAH13289 BT006721 AAP35367 BX641053 DQ786191 U50743 AAB09425 NM_001680 NP_001671 NM_021603 NP_067614 NM_001127489 |
| Function | May be involved in forming the receptor site for cardiac glycoside binding or may modulate the transport function of the sodium ATPase. |
| Subcellular Location | Membrane {ECO:0000305}; Single-pass type III membrane protein {ECO:0000305}. |
| Tissue Specificity | Expressed in the distal convoluted tubule in the kidney. Found on basolateral membranes of nephron epithelial cells. |
| Top Pathways | Salivary secretion, Cardiac muscle contraction, cAMP signaling pathway, Aldosterone-regulated sodium reabsorption, Thyroid hormone synthesis |