Gene Symbol | FXYD2 |
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Entrez Gene | 486 |
Alt Symbol | ATP1G1, HOMG2 |
Species | Human |
Gene Type | protein-coding |
Description | FXYD domain containing ion transport regulator 2 |
Other Description | ATPase, Na+/K+ transporting, gamma 1 polypeptide|Na(+)/K(+) ATPase subunit gamma|sodium pump gamma chain|sodium/potassium-transporting ATPase subunit gamma |
Swissprots | Q9GZQ7 P54710 Q15332 Q9GZP3 Q53YC1 |
Accessions | AAG34359 AAG34360 AAG37906 AAG37907 EAW67325 EAW67326 P54710 AA309757 AA814197 AF241236 AAG34361 AK096069 BAC04693 BC005302 AAH05302 BC013289 AAH13289 BT006721 AAP35367 BX641053 DQ786191 U50743 AAB09425 NM_001680 NP_001671 NM_021603 NP_067614 NM_001127489 |
Function | May be involved in forming the receptor site for cardiac glycoside binding or may modulate the transport function of the sodium ATPase. |
Subcellular Location | Membrane {ECO:0000305}; Single-pass type III membrane protein {ECO:0000305}. |
Tissue Specificity | Expressed in the distal convoluted tubule in the kidney. Found on basolateral membranes of nephron epithelial cells. |
Top Pathways | Salivary secretion, Cardiac muscle contraction, cAMP signaling pathway, Aldosterone-regulated sodium reabsorption, Thyroid hormone synthesis |
FXYD2 CRISPR/Cas9 KO Plasmid (h) - sc-404044 from Santa Cruz Biotechnology
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FXYD2 HDR Plasmid (h) - sc-404044-HDR from Santa Cruz Biotechnology
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FXYD2 Double Nickase Plasmid (h) - sc-404044-NIC from Santa Cruz Biotechnology
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FXYD2 Double Nickase Plasmid (h2) - sc-404044-NIC-2 from Santa Cruz Biotechnology
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FXYD2 CRISPR Activation Plasmid (h) - sc-404044-ACT from Santa Cruz Biotechnology
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FXYD2 CRISPR Activation Plasmid (h2) - sc-404044-ACT-2 from Santa Cruz Biotechnology
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FXYD2 Lentiviral Activation Particles (h) - sc-404044-LAC from Santa Cruz Biotechnology
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FXYD2 Lentiviral Activation Particles (h2) - sc-404044-LAC-2 from Santa Cruz Biotechnology
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FXYD2 siRNA (h) - sc-42422 from Santa Cruz Biotechnology
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FXYD2 shRNA Plasmid (h) - sc-42422-SH from Santa Cruz Biotechnology
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FXYD2 shRNA (h) Lentiviral Particles - sc-42422-V from Santa Cruz Biotechnology
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FXYD2 RNAi - H00000486-R04 from Novus Biologicals
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FXYD2 RNAi - H00000486-R03 from Novus Biologicals
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MISSION® esiRNA - EHU135501 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9012 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9012 from Sigma-Aldrich
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FXYD2 siRNA (Human) - CRH0340 from Cohesion Biosciences
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FXYD2 - MBS8233349 from MyBioSource
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shRNA set against Human FXYD2 (NM_001680.4) - SHH297933 from Creative biogene
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Human FXYD2 siRNA - orb260842 from Biorbyt
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FXYD2 shRNA Plasmid (Human) - CHH0340 from Cohesion Biosciences
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FXYD2 miRNA 3'UTR clone - MiUTR3H-04431 from Creative biogene
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FXYD2 miRNA 3'UTR clone - MiUTR3H-04432 from Creative biogene
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