| Gene Symbol |
KRTAP7-1
|
| Entrez Gene |
337878
|
| Alt Symbol |
KAP7.1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
keratin associated protein 7-1 (gene/pseudogene)
|
| Other Description |
high tyrosine-glycine keratin-associated protein 7.1|keratin-associated protein 7-1
|
| Swissprots |
Q8IUC3 Q3LI56
|
| Accessions |
Q8IUC3 AB096962 BAE46377 AJ457063 CAD29719 NM_181606 NP_853637
|
| Function |
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins.
|
| Tissue Specificity |
Expressed in the upper portion of the hair cortex.
|