| Gene Symbol |
POGZ
|
| Entrez Gene |
23126
|
| Alt Symbol |
ZNF280E, ZNF635, ZNF635m
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
pogo transposable element with ZNF domain
|
| Other Description |
putative protein product of Nbla00003|zinc finger protein 280E|zinc finger protein 635
|
| Swissprots |
Q5SZS3 Q5SZS1 Q5SZS2 O75049 Q5SZS4 Q3LIC4 B4DYL9 B4DTP8 Q7Z3K3 Q8TDZ7 E9PM80 Q9Y4X7 B7ZBY5
|
| Accessions |
EAW53436 EAW53437 EAW53438 EAW53439 EAW53440 EAW53441 Q7Z3K3 AB007930 BAA32306 AB037911 BAB87117 AB075477 BAE45744 AJ242979 CAB45136 AK000199 AK299791 BAG61670 AK300307 BAG62060 AK302501 BAG63781 AM392919 CAL37797 AW167360 BC042018 BC057773 AAH57773 BC166671 AAI66671 BX537561 BX537838 CAD97850 BX649163 XM_005244999 XP_005245056 XM_005245000 XP_005245057 XM_005245001 XP_005245058 XM_005245005 XP_005245062 XM_005245006 XP_005245063 XM_011509330 XP_011507632 XM_011509331 XP_011507633 XR_921760 NM_001194937 NP_001181866 NM_001194938 NP_001181867 NM_015100 NP_055915 NM_145796 NP_665739 NM_207171 NP_997054
|
| Function |
Plays a role in mitotic cell cycle progression and is involved in kinetochore assembly and mitotic sister chromatid cohesion. Probably through its association with CBX5 plays a role in mitotic chromosome segregation by regulating aurora kinase B/AURKB activation and AURKB and CBX5 dissociation from chromosome arms. {ECO:0000269|PubMed:20562864}.
|
| Subcellular Location |
Nucleus. Chromosome. Cytoplasm. Note=According to some authors, it is not localized to mitotic chromatin (PubMed:19244240). Recruited to trimethylated 'Lys-9' of histone H3 (H3K9me3). {ECO:0000269|PubMed:19244240}.
|