| Gene Symbol |
SLC37A4
|
| Entrez Gene |
2542
|
| Alt Symbol |
G6PT1, G6PT2, G6PT3, GSD1b, GSD1c, GSD1d, PRO0685, TRG-19, TRG19
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
solute carrier family 37 (glucose-6-phosphate transporter), member 4
|
| Other Description |
glucose-5-phosphate transporter|glucose-6-phosphatase, transport (glucose) protein 3|glucose-6-phosphatase, transport (glucose-6-phosphate) protein 1|glucose-6-phosphatase, transport (phosphate/pyrophosphate) protein 2|glucose-6-phosphate translocase|microsomal glucose-6-phosphate transporter|transformation-related gene 19 protein
|
| Swissprots |
O43826 O96016 Q9UNS4 Q9UI19 Q5J7V4
|
| Accessions |
AAC72916 AAD13111 AAD19898 CAA76898 EAW67432 EAW67433 EAW67434 EAW67435 EAW67436 EAW67437 EAW67438 EAW67439 O43826 AB209026 BAD92263 AF110819 AAF37735 AF110820 AAF37736 AF110821 AF110822 AF111852 AAF16691 AK289642 BAF82331 AK294993 BAH11943 AK298395 BAG60630 AK300646 BAG62334 AK312628 AY423732 AAS00495 BC002400 AAH02400 BC003589 AAH03589 BC014663 AAH14663 BC015650 AAH15650 BC064563 AAH64563 BM506735 CR456733 CAG33014 DA485567 DC295438 HQ448291 ADQ32771 Y15409 CAA75608 NM_001164277 NP_001157749 NM_001164278 NP_001157750 NM_001164279 NP_001157751 NM_001164280 NP_001157752 NM_001467 NP_001458
|
| Function |
Transports glucose-6-phosphate from the cytoplasm to the lumen of the endoplasmic reticulum. Forms with glucose-6- phosphatase the complex responsible for glucose production through glycogenolysis and gluconeogenesis. Hence, it plays a central role in homeostatic regulation of blood glucose levels. {ECO:0000269|PubMed:10026167}.
|
| Subcellular Location |
Endoplasmic reticulum membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
|
| Tissue Specificity |
Mostly expressed in liver and kidney.
|
| Top Pathways |
Carbohydrate digestion and absorption
|