Gene Symbol | WLS |
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Entrez Gene | 79971 |
Alt Symbol | C1orf139, EVI, GPR177, MRP, mig-14 |
Species | Human |
Gene Type | protein-coding |
Description | wntless Wnt ligand secretion mediator |
Other Description | G protein-coupled receptor 177|integral membrane protein GPR177|protein evenness interrupted homolog|protein wntless homolog|putative NF-kappa-B-activating protein 373|putative NFkB activating protein 373 |
Swissprots | B2RNT2 Q5T9L3 Q8NC43 Q7Z2Z9 Q5JRS7 |
Accessions | CAF86190 CCQ43006 EAX06479 EAX06480 EAX06481 Q5T9L3 AB097018 BAC77371 AI217373 AK026744 BAB15540 AK074583 BAC11072 AK074984 BAC11333 AK301613 BAH13523 AK309779 AW137622 AY359035 AAQ89394 BC007211 AAH07211 BC110826 AAI10827 BC137109 AAI37110 BC137113 AAI37114 BG701224 BX537492 BX538320 CAD98094 BX648748 CA438784 DA753300 DB478499 DQ323735 ABD58927 XM_011542191 XP_011540493 XM_011542192 XP_011540494 NM_001002292 NP_001002292 NM_001193334 NP_001180263 NM_024911 NP_079187 |
Function | Regulates Wnt proteins sorting and secretion in a feedback regulatory mechanism. This reciprocal interaction plays a key role in the regulation of expression, subcellular location, binding and organelle-specific association of Wnt proteins. Plays also an important role in establishment of the anterior-posterior body axis formation during development (By similarity). {ECO:0000250}. |
Subcellular Location | Golgi apparatus membrane {ECO:0000269|PubMed:16678095}; Multi-pass membrane protein {ECO:0000269|PubMed:16678095}. Cytoplasmic vesicle membrane {ECO:0000269|PubMed:16678095}; Multi-pass membrane protein {ECO:0000269|PubMed:16678095}. |
Human GPR177 protein fragment - ab140720 from Abcam
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GPR177/WLS Partial Recombinant Protein - H00079971-Q01 from Novus Biologicals
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Recombinant Human GPR177/WLS Protein - NBP2-22947 from Novus Biologicals
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Human WLS protein - orb169559 from Biorbyt
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Eosinophil Peroxidase protein - 30-1101 from Fitzgerald
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Eosinophil protein - 30-1102 from Fitzgerald
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GPR177 Blocking Peptide - 33R-2005 from Fitzgerald
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GPR177 Blocking Peptide - 33R-1477 from Fitzgerald
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WLS protein (His tag) - 80R-2719 from Fitzgerald
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MRP Blocking Peptide - abx161170 from Abbexa
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GPR177 (101-232, His-tag) - AR50839PU-N from Acris Antibodies
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GPR177 (101-232, His-tag) - AR50839PU-S from Acris Antibodies
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GPR177 - H00079971-Q01-10 from Acris Antibodies
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GPR177 - H00079971-Q01-25 from Acris Antibodies
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WLS, 101-232aa, Human, His tag, E.coli - 01-P2015 from ARP American Research Products
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GPR177 fusion protein - Ag12446 from Proteintech Group
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GPR177 fusion protein - ag12428 from Proteintech Group
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WLS Human - PRPS-1409 from NeoScientific
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Recombinant Human GPR177, His-tagged - GPR177-13465H from Creative Biomart
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Recombinant Human WLS, His-tagged - WLS-7571H from Creative Biomart
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WLS, Recombinant Protein - MBS205242 from MyBioSource
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Wntless , Recombinant Protein - MBS145611 from MyBioSource
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WLS Peptide, Human - M34GP17506H from Creative Peptides
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WLS - PAT-82014-1 from Nordic BioSite
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WLS - PAT-82014-2 from Nordic BioSite
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