Gene Symbol | MCFD2 |
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Entrez Gene | 90411 |
Alt Symbol | F5F8D, F5F8D2, LMAN1IP, SDNSF |
Species | Human |
Gene Type | protein-coding |
Description | multiple coagulation factor deficiency 2 |
Other Description | multiple coagulation factor deficiency protein 2|neural stem cell-derived neuronal survival protein |
Swissprots | Q8N3M5 D6W5A9 A8K7W2 Q8NI22 Q68D61 E9PD95 Q53SS3 |
Accessions | AAY15013 CAJ44943 CBF57596 EAX00230 EAX00231 EAX00232 EAX00233 Q8NI22 AF475284 AAM28465 AF537214 AAP23162 AI079820 AI371370 AK095006 AK292127 BAF84816 AK293889 BAG57278 AL833900 CAD38756 BC037845 AAH37845 BC040357 AAH40357 BI553070 CF994192 CR749562 CAH18359 DA194356 DA226366 DA324623 DA330030 DA404031 DA412975 DB096245 DC321899 DC332658 DQ891104 ABM82030 DQ894285 ABM85211 M23161 NM_001171506 NP_001164977 NM_001171507 NP_001164978 NM_001171508 NP_001164979 NM_001171509 NP_001164980 NM_001171510 NP_001164981 NM_001171511 NP_001164982 NM_139279 NP_644808 |
Function | The MCFD2-LMAN1 complex forms a specific cargo receptor for the ER-to-Golgi transport of selected proteins. Plays a role in the secretion of coagulation factors. {ECO:0000269|PubMed:12717434}. |
Subcellular Location | Endoplasmic reticulum-Golgi intermediate compartment {ECO:0000269|PubMed:12717434}. Endoplasmic reticulum {ECO:0000269|PubMed:12717434}. Golgi apparatus {ECO:0000269|PubMed:12717434}. |
MCFD2 CRISPR/Cas9 KO Plasmid (h) - sc-408994 from Santa Cruz Biotechnology
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MCFD2 HDR Plasmid (h) - sc-408994-HDR from Santa Cruz Biotechnology
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MCFD2 Double Nickase Plasmid (h) - sc-408994-NIC from Santa Cruz Biotechnology
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MCFD2 Double Nickase Plasmid (h2) - sc-408994-NIC-2 from Santa Cruz Biotechnology
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MCFD2 CRISPR Activation Plasmid (h) - sc-408994-ACT from Santa Cruz Biotechnology
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MCFD2 CRISPR Activation Plasmid (h2) - sc-408994-ACT-2 from Santa Cruz Biotechnology
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MCFD2 Lentiviral Activation Particles (h) - sc-408994-LAC from Santa Cruz Biotechnology
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MCFD2 Lentiviral Activation Particles (h2) - sc-408994-LAC-2 from Santa Cruz Biotechnology
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MCFD2 siRNA (h) - sc-44445 from Santa Cruz Biotechnology
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MCFD2 shRNA Plasmid (h) - sc-44445-SH from Santa Cruz Biotechnology
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MCFD2 shRNA (h) Lentiviral Particles - sc-44445-V from Santa Cruz Biotechnology
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SDNSF/MCFD2 RNAi - H00090411-R01V from Novus Biologicals
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SDNSF/MCFD2 RNAi - H00090411-R01 from Novus Biologicals
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MISSION® esiRNA - EHU105371 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN13112 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND13112 from Sigma-Aldrich
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MCFD2 siRNA (Human) - CRJ3943 from Cohesion Biosciences
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shRNA set against Human MCFD2 (NM_139279.5) - SHH339223 from Creative biogene
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Human MCFD2 siRNA - orb274444 from Biorbyt
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MCFD2 shRNA Plasmid (Human) - CHJ3943 from Cohesion Biosciences
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MCFD2 miRNA 3'UTR clone - MiUTR4H-TG05408 from Creative biogene
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