| Gene Symbol |
SLC43A2
|
| Entrez Gene |
124935
|
| Alt Symbol |
LAT4
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
solute carrier family 43 (amino acid system L transporter), member 2
|
| Other Description |
L-type amino acid transporter 4|amino acid transporter|large neutral amino acids transporter small subunit 4|solute carrier family 43, member 2
|
| Swissprots |
Q8NC21 C9JNU8 Q8NBX1 Q6IPM1 B7Z6X9 Q8WZ00 Q8N370 Q5CD75 D3DTH9
|
| Accessions |
EAW90601 EAW90602 EAW90603 EAW90604 EAW90605 EAW90606 EAW90607 Q8N370 AB120364 BAD91091 AF289592 AAL55776 AK056769 AK074428 AK075068 BAC11383 AK075173 BAC11450 AK075196 BAC11464 AK301127 BAH13415 BC019562 AAH19562 BC027923 AAH27923 BC071859 AAH71859 BK005642 DAA05676 DC381982 HY089501 N26925 XM_011523645 XP_011521947 XM_011523646 XP_011521948 XM_011523647 XP_011521949 XM_011523648 XP_011521950 XR_933972 NM_001284498 NP_001271427 NM_001284499 NP_001271428 NM_152346 NP_689559
|
| Function |
Sodium-, chloride-, and pH-independent high affinity transport of large neutral amino acids. {ECO:0000269|PubMed:15659399}.
|
| Subcellular Location |
Membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
|
| Tissue Specificity |
Detected in several tissues with higher expression in placenta, kidney and peripheral blood leukocytes. In the kidney, is detected in epithelial cells of the distal tubule and collecting duct. In the intestine, is expressed mainly in crypt cells of the intestinal microvilli and epithelial cells in the base of the villus. {ECO:0000269|PubMed:15659399}.
|
![Western Blot: SLC43A2 Overexpression Lysate (Adult Normal) [NBL1-16158] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for SLC43A2.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/1372_SLC43A2%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-16158-img0002.jpg)