| Gene Symbol |
GTF3C4
|
| Entrez Gene |
9329
|
| Alt Symbol |
KAT12, TFIII90, TFIIIC290, TFIIIC90, TFIIICDELTA
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
general transcription factor IIIC, polypeptide 4, 90kDa
|
| Other Description |
TF3C-delta|TFIIIC 90 kDa subunit|general transcription factor 3C 4|general transcription factor 3C polypeptide 4|transcription factor IIIC 90 kDa subunit|transcription factor IIIC subunit delta
|
| Swissprots |
Q5VZJ7 Q9UKN8
|
| Accessions |
EAW88010 EAW88011 Q9UKN8 AF142328 AAF05087 AK024655 AK027509 BAG51334 BC011619 AAH11619 BC022787 AAH22787 BC060821 BC094774 AAH94774 BC104755 AAI04756 BC112245 AAI12246 CX755755 XR_929875 NM_012204 NP_036336
|
| Function |
Essential for RNA polymerase III to make a number of small nuclear and cytoplasmic RNAs, including 5S RNA, tRNA, and adenovirus-associated (VA) RNA of both cellular and viral origin. Has histone acetyltransferase activity (HAT) with unique specificity for free and nucleosomal H3. May cooperate with GTF3C5 in facilitating the recruitment of TFIIIB and RNA polymerase through direct interactions with BRF1, POLR3C and POLR3F. May be localized close to the A box.
|
| Subcellular Location |
Nucleus.
|