Gene Symbol | SETD3 |
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Entrez Gene | 84193 |
Alt Symbol | C14orf154 |
Species | Human |
Gene Type | protein-coding |
Description | SET domain containing 3 |
Other Description | SET domain-containing protein 3|histone-lysine N-methyltransferase setd3 |
Swissprots | Q0VAQ2 A5PLP0 Q9H5U5 B4DZE8 Q659C0 Q86TU7 Q96GY9 A0PJU3 Q86TU8 |
Accessions | EAW81664 EAW81665 EAW81666 EAW81667 Q86TU7 AK026680 BAB15525 AK302882 BAG64060 AL359581 CAH56365 BC009054 AAH09054 BC037395 BC066931 AAH66931 BC120967 AAI20968 BC120968 AAI20969 BC127624 AAI27625 BC127625 AAI27626 BC142995 AAI42996 BC148251 AAI48252 BG194029 BX161441 CAD61911 BX161471 CAD61927 CB988965 XM_005268127 XP_005268184 XM_011537231 XP_011535533 XM_011537232 XP_011535534 XM_011537233 XP_011535535 XM_011537234 XP_011535536 XM_011537235 XP_011535537 NM_032233 NP_115609 NM_199123 NP_954574 |
Function | Histone methyltransferase that methylates 'Lys-4' and 'Lys-36' of histone H3 (H3K4me and H3K36me). Acts as a transcriptional activator. Plays an important role in the transcriptional regulation of muscle cell differentiation via interaction with MYOD1. {ECO:0000250|UniProtKB:Q91WC0}. |
Subcellular Location | Nucleus {ECO:0000250|UniProtKB:Q91WC0}. |
SETD3 CRISPR/Cas9 KO Plasmid (h) - sc-410191 from Santa Cruz Biotechnology
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SETD3 HDR Plasmid (h) - sc-410191-HDR from Santa Cruz Biotechnology
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SETD3 Double Nickase Plasmid (h) - sc-410191-NIC from Santa Cruz Biotechnology
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SETD3 Double Nickase Plasmid (h2) - sc-410191-NIC-2 from Santa Cruz Biotechnology
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SETD3 CRISPR Activation Plasmid (h) - sc-410191-ACT from Santa Cruz Biotechnology
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SETD3 CRISPR Activation Plasmid (h2) - sc-410191-ACT-2 from Santa Cruz Biotechnology
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SETD3 Lentiviral Activation Particles (h) - sc-410191-LAC from Santa Cruz Biotechnology
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SETD3 Lentiviral Activation Particles (h2) - sc-410191-LAC-2 from Santa Cruz Biotechnology
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SETD3 siRNA (h) - sc-92438 from Santa Cruz Biotechnology
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SETD3 shRNA Plasmid (h) - sc-92438-SH from Santa Cruz Biotechnology
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SETD3 shRNA (h) Lentiviral Particles - sc-92438-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU089591 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN19168 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19168 from Sigma-Aldrich
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SETD3 siRNA (Human) - CRJ3347 from Cohesion Biosciences
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SETD3 - MBS8227683 from MyBioSource
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shRNA set against Human SETD3 (NM_199123.1) - SHH405596 from Creative biogene
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shRNA set against Human SETD3(NM_032233.2) - SHR218392 from Creative biogene
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shRNA set against Human SETD3(NM_199123.1) - SHR218496 from Creative biogene
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shRNA set against Human SETD3(NM_032233.2) - SHR218532 from Creative biogene
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Human SETD3 siRNA - orb273848 from Biorbyt
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SETD3 shRNA Plasmid (Human) - CHJ3347 from Cohesion Biosciences
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SETD3 miRNA 3'UTR clone - MiUTR1H-09311 from Creative biogene
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SETD3 miRNA 3'UTR clone - MiUTR1H-09312 from Creative biogene
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