Gene Symbol | gdf3 |
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Entrez Gene | 394305 |
Alt Symbol | der, derriere, gdf3-a, vgr-2, vgr2 |
Species | Xenopus |
Gene Type | protein-coding |
Description | growth differentiation factor 3 |
Other Description | derriA re|derriere (posterior determination, TGFb family member)|derriere (tgf-beta family member)|derriere protein|gdf-3 |
Swissprots | Q8JH95 Q9YGV1 |
Accessions | Q9YGV1 AF065135 AAD19837 BC073508 AAH73508 NM_001087497 NP_001080966 |
Function | Required for posterior mesoderm formation during embryogenesis. Acts indirectly to suppress head formation by altering mesodermal patterning. Also involved in the establishment of left-right axis asymmetry, acting upstream of nodal/nr-1. Can exert long-range effects in the embryo. {ECO:0000269|PubMed:10068640, ECO:0000269|PubMed:11256621, ECO:0000269|PubMed:12070085, ECO:0000269|PubMed:12361977}. |
Subcellular Location | Secreted {ECO:0000269|PubMed:11256621}. |
Tissue Specificity | Initially expressed throughout the presumptive embryonic mesendoderm with subsequent localization to the posterior mesoderm. {ECO:0000269|PubMed:10068640, ECO:0000269|PubMed:12070085}. |
Recombinant Xenopus laevis Derriere protein(derriere) - CSB-YP897418XBE CSB-EP897418XBE CSB-BP897418XBE CSB-MP897418XBE from Cusabio
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Derriere protein (derriere), Recombinant Protein - MBS1390050 from MyBioSource
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Derriere protein (derriere), Recombinant Protein - MBS1412846 from MyBioSource
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