Gene Symbol | SEPT12 |
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Entrez Gene | 124404 |
Alt Symbol | SPGF10 |
Species | Human |
Gene Type | protein-coding |
Description | septin 12 |
Other Description | septin-12 |
Swissprots | Q1PBH0 Q0P6B0 Q96LL0 Q8IYM1 |
Accessions | CCQ42950 EAW85264 EAW85265 Q8IYM1 AI554914 AK058139 BAB71681 AK098718 BC024017 AAH24017 BC035619 AAH35619 DQ456996 ABE68946 DQ517531 ABF61438 EF620906 ABR10901 HQ447801 ADQ32285 XM_006720846 XP_006720909 XM_011522379 XP_011520681 NM_001154458 NP_001147930 NM_144605 NP_653206 |
Function | Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential). {ECO:0000250, ECO:0000305}. |
Subcellular Location | Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle. Cell projection, cilium, flagellum. Note=At interphase, forms a filamentous structure in the cytoplasm. During anaphase, translocates to the central spindle region and to the midbody during cytokinesis. Found in the sperm annulus. |
Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:15915442}. |
Top Pathways | Bacterial invasion of epithelial cells |
Septin 12 CRISPR/Cas9 KO Plasmid (h) - sc-410274 from Santa Cruz Biotechnology
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Septin 12 HDR Plasmid (h) - sc-410274-HDR from Santa Cruz Biotechnology
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Septin 12 Double Nickase Plasmid (h) - sc-410274-NIC from Santa Cruz Biotechnology
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Septin 12 Double Nickase Plasmid (h2) - sc-410274-NIC-2 from Santa Cruz Biotechnology
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Septin 12 CRISPR Activation Plasmid (h) - sc-410274-ACT from Santa Cruz Biotechnology
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Septin 12 CRISPR Activation Plasmid (h2) - sc-410274-ACT-2 from Santa Cruz Biotechnology
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Septin 12 Lentiviral Activation Particles (h) - sc-410274-LAC from Santa Cruz Biotechnology
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Septin 12 Lentiviral Activation Particles (h2) - sc-410274-LAC-2 from Santa Cruz Biotechnology
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Septin 12 siRNA (h) - sc-93540 from Santa Cruz Biotechnology
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Septin 12 shRNA Plasmid (h) - sc-93540-SH from Santa Cruz Biotechnology
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Septin 12 shRNA (h) Lentiviral Particles - sc-93540-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU153631 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN19101 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19101 from Sigma-Aldrich
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SEPT12 siRNA (Human) - CRJ4761 from Cohesion Biosciences
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SEPT12 - MBS8221550 from MyBioSource
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shRNA set against Human SEPT12 (NM_144605.4) - SHH404617 from Creative biogene
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SEPT12 shRNA Plasmid (Human) - CHJ4761 from Cohesion Biosciences
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SEPT12 miRNA 3'UTR clone - MiUTR4H-TG07933 from Creative biogene
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