Gene Symbol | LMX1B |
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Entrez Gene | 4010 |
Alt Symbol | LMX1.2, NPS1 |
Species | Human |
Gene Type | protein-coding |
Description | LIM homeobox transcription factor 1, beta |
Other Description | LIM homeobox transcription factor 1-beta|LIM/homeobox protein 1.2|LIM/homeobox protein LMX1B|LMX-1.2 |
Swissprots | Q5JU95 Q6ISC9 O60663 O75463 F8W7W6 |
Accessions | AAC27294 EAW87641 EAW87642 O60663 AF057135 AAC39738 BC069588 AAH69588 BC069601 AAH69601 BC112120 AAI12121 BC113491 AAI13492 BC143801 AAI43802 EL952935 HG502432 HQ258228 ADR82982 HQ447493 ADQ31979 U77457 AAC13544 NM_001174146 NP_001167617 NM_001174147 NP_001167618 NM_002316 NP_002307 |
Function | Essential for the specification of dorsal limb fate at both the zeugopodal and autopodal levels. |
Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108}. |
Tissue Specificity | Expressed in most tissues. Highest levels in testis, thyroid, duodenum, skeletal muscle, and pancreatic islets. |
LMX1B CRISPR/Cas9 KO Plasmid (h) - sc-402945 from Santa Cruz Biotechnology
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LMX1B HDR Plasmid (h) - sc-402945-HDR from Santa Cruz Biotechnology
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LMX1B Double Nickase Plasmid (h) - sc-402945-NIC from Santa Cruz Biotechnology
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LMX1B Double Nickase Plasmid (h2) - sc-402945-NIC-2 from Santa Cruz Biotechnology
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LMX1B CRISPR Activation Plasmid (h) - sc-402945-ACT from Santa Cruz Biotechnology
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LMX1B CRISPR Activation Plasmid (h2) - sc-402945-ACT-2 from Santa Cruz Biotechnology
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LMX1B Lentiviral Activation Particles (h) - sc-402945-LAC from Santa Cruz Biotechnology
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LMX1B Lentiviral Activation Particles (h2) - sc-402945-LAC-2 from Santa Cruz Biotechnology
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LMX1B siRNA (h) - sc-38721 from Santa Cruz Biotechnology
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LMX1B shRNA Plasmid (h) - sc-38721-SH from Santa Cruz Biotechnology
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LMX1B shRNA (h) Lentiviral Particles - sc-38721-V from Santa Cruz Biotechnology
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LMX1b RNAi - H00004010-R01 from Novus Biologicals
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MISSION® esiRNA - EHU145821 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN11784 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11784 from Sigma-Aldrich
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LMX1B siRNA (Human) - CRH2715 from Cohesion Biosciences
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LMX1B CRISPR/Cas9 KO Plasmid (h2) - sc-402945-KO-2 from Santa Cruz Biotechnology
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LMX1B HDR Plasmid (h2) - sc-402945-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human LMX1B (NM_002316.3) - SHH331159 from Creative biogene
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Human LMX1B siRNA - orb263217 from Biorbyt
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LMX1B shRNA Plasmid (Human) - CHH2715 from Cohesion Biosciences
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