Gene Symbol |
Hyal1
|
Entrez Gene |
367166
|
Alt Symbol |
-
|
Species |
Rat
|
Gene Type |
protein-coding
|
Description |
hyaluronoglucosaminidase 1
|
Other Description |
hyal-1|hyaluronidase 1|hyaluronidase-1|hyaluronoglucosaminidase-1
|
Swissprots |
Q76HN1
|
Accessions |
EDL77243 Q76HN1 AB100600 BAD14368 NM_207616 NP_997499
|
Function |
May have a role in promoting tumor progression. May block the TGFB1-enhanced cell growth (By similarity). Overexpression of HYAL1 suppressed the growth rate of colon carcinoma cell tumors in an experimental model. {ECO:0000250, ECO:0000269|PubMed:12397638}.
|
Subcellular Location |
Secreted {ECO:0000250}. Lysosome {ECO:0000250}.
|
Top Pathways |
Lysosome, Glycosaminoglycan degradation
|