| Gene Symbol |
ANAPC7
|
| Entrez Gene |
51434
|
| Alt Symbol |
APC7
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
anaphase promoting complex subunit 7
|
| Other Description |
anaphase-promoting complex subunit 7|cyclosome subunit 7
|
| Swissprots |
Q9NT16 Q9BU24 Q9UJX3 Q96AC4 Q96GF4
|
| Accessions |
EAW97909 EAW97910 EAW97911 Q9UJX3 AF191340 AAF05754 AK021809 BAG51054 AL137586 CAB70828 AL157481 CAH10690 AY007104 BC002941 AAH02941 BC009498 AAH09498 BC017316 AAH17316 BC040130 BC098264 AAH98264 BC098295 AAH98295 BC098362 AAH98362 BC099732 AAH99732 BC111798 AAI11799 BC141848 AAI41849 BC148236 AAI48237 BG105587 DB003237 XM_005253903 XP_005253960 XM_011538454 XP_011536756 XR_243015 NM_001137664 NP_001131136 NM_016238 NP_057322
|
| Function |
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. {ECO:0000269|PubMed:18485873}.
|
| Top Pathways |
Cell cycle, Ubiquitin mediated proteolysis, Progesterone-mediated oocyte maturation, Oocyte meiosis, HTLV-I infection
|