Gene Symbol | NDUFB6 |
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Entrez Gene | 4712 |
Alt Symbol | B17, CI |
Species | Human |
Gene Type | protein-coding |
Description | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa |
Other Description | CI-B17|NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6|NADH-ubiquinone oxidoreductase B17 subunit|NADH-ubiquinone oxidoreductase beta subunit, 6|complex I, mitochondrial respiratory chain, B17 subunit|complex I-B17 |
Swissprots | Q6IB84 O95139 Q5VYT2 A8K0Y7 |
Accessions | EAW58541 EAW58542 EAW58543 O95139 AF035840 AAC68838 AF067167 AAD32451 AK092649 AK289702 BAF82391 AW160372 BC009801 AAH09801 BC016708 BC029247 AAH29247 BG220924 BI669356 BP208846 BU952486 CB140469 CR456920 CAG33201 NM_001199987 NP_001186916 NM_002493 NP_002484 NM_182739 NP_877416 |
Function | Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. |
Subcellular Location | Mitochondrion inner membrane; Single-pass membrane protein; Matrix side. |
Top Pathways | Alzheimer's disease, Huntington's disease, Non-alcoholic fatty liver disease (NAFLD), Oxidative phosphorylation |
NDUFB6 CRISPR/Cas9 KO Plasmid (h) - sc-416283 from Santa Cruz Biotechnology
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NDUFB6 HDR Plasmid (h) - sc-416283-HDR from Santa Cruz Biotechnology
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NDUFB6 Double Nickase Plasmid (h) - sc-416283-NIC from Santa Cruz Biotechnology
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NDUFB6 Double Nickase Plasmid (h2) - sc-416283-NIC-2 from Santa Cruz Biotechnology
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NDUFB6 CRISPR Activation Plasmid (h) - sc-416283-ACT from Santa Cruz Biotechnology
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NDUFB6 CRISPR Activation Plasmid (h2) - sc-416283-ACT-2 from Santa Cruz Biotechnology
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NDUFB6 Lentiviral Activation Particles (h) - sc-416283-LAC from Santa Cruz Biotechnology
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NDUFB6 Lentiviral Activation Particles (h2) - sc-416283-LAC-2 from Santa Cruz Biotechnology
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NDUFB6 siRNA (h) - sc-92468 from Santa Cruz Biotechnology
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NDUFB6 shRNA Plasmid (h) - sc-92468-SH from Santa Cruz Biotechnology
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NDUFB6 shRNA (h) Lentiviral Particles - sc-92468-V from Santa Cruz Biotechnology
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NDUFB6 RNAi - H00004712-R02 from Novus Biologicals
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MISSION® esiRNA - EHU115421 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN15160 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15160 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR02867 from Sigma-Aldrich
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NDUFB6 siRNA (Human) - CRH3126 from Cohesion Biosciences
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NDUFB6 RNAi - H00004712-R01 from Novus Biologicals
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shRNA set against Human NDUFB6 (NM_182739.2) - SHH350768 from Creative biogene
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Human NDUFB6 siRNA - orb263628 from Biorbyt
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NDUFB6 shRNA Plasmid (Human) - CHH3126 from Cohesion Biosciences
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NDUFB6 miRNA 3'UTR clone - MiUTR3H-05858 from Creative biogene
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NDUFB6 miRNA 3'UTR clone - MiUTR3H-05859 from Creative biogene
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