| Gene Symbol |
B3GALNT1
|
| Entrez Gene |
8706
|
| Alt Symbol |
B3GALT3, GLCT3, GLOB, Gb4Cer, P, P1, beta3Gal-T3, galT3
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
|
| Other Description |
P antigen synthase|P blood group globoside|UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 3 (Globoside blood group)|UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1|UDP-GalNAc:betaGlcNAc beta-1,3-galactosaminyltransferase, polypeptide 1 (Globoside blood group)|UDP-N-acetylgalactosamine:globotriaosylceramide beta-1,3-N-acetylgalactosaminyltransferase|b3Gal-T3|beta-1,3-GalNAc-T1|beta-1,3-GalTase 3|beta-1,3-galactosyltransferase 3|beta-3-Gx-T3|beta3GalT3|brainiac1|galactosylgalactosylglucosylceramide beta-D-acetyl-galactosaminyltransferase|globoside synthase|globotriaosylceramide 3-beta-N-acetylgalactosaminyltransferase
|
| Swissprots |
D3DNM4 O75752 Q9HA06 Q8NFM9 Q6IAI5 Q8NFM8 Q3Y531
|
| Accessions |
AAM96009 AAM96010 AAM96011 AAM96012 AAS79228 AAS79229 AAS79230 AAS79231 AAZ67917 CCB78511 CCB78512 CCB78513 CCB78514 EAW78621 EAW78622 EAW78623 EAW78624 EAW78625 O75752 AB050855 BAB17690 AB050856 BAB17691 AB060691 BAB91079 AF132731 AAF66442 AF154848 AAF72106 AI093705 AI214215 AK022491 BAB14055 AK095917 BAG53166 AK223439 BAD97159 AK295552 BAG58456 AW151434 AY359049 AAQ89408 BC028571 AAH28571 BC047618 AAH47618 CR457170 CAG33451 DA188324 DB172381 HQ448022 ADQ32503 Y15062 CAA75346 XM_005247859 XP_005247916 XM_005247861 XP_005247918 XM_005247862 XP_005247919 XM_005247864 XP_005247921 XM_006713803 XP_006713866 XM_006713804 XP_006713867 XM_006713805 XP_006713868 XM_011513261 XP_011511563 XM_011513262 XP_011511564 NM_001038628 NP_001033717 NM_003781 NP_003772 NM_033167 NP_149357 NM_033168 NP_149358 NM_033169 NP_149359
|
| Function |
Transfers N-acetylgalactosamine onto globotriaosylceramide. {ECO:0000269|PubMed:10993897}.
|
| Subcellular Location |
Golgi apparatus membrane; Single-pass type II membrane protein.
|
| Tissue Specificity |
Higher expression in heart and brain, and to a lesser extent in lung, placenta, kidney and testis. Lower expression in liver, spleen and stomach. No expression in skeletal muscle. {ECO:0000269|PubMed:10993897, ECO:0000269|PubMed:9582303}.
|
| Top Pathways |
Glycosphingolipid biosynthesis - globo series
|