Tyrp1
| Gene Symbol | Tyrp1 |
|---|---|
| Entrez Gene | 22178 |
| Alt Symbol | Oca3, TRP-1, TRP1, Tyrp, b, brown, isa |
| Species | Mouse |
| Gene Type | protein-coding |
| Description | tyrosinase-related protein 1 |
| Other Description | 5,6-dihydroxyindole-2-carboxylic acid oxidase|DHICA oxidase|brown locus protein|catalase B|iris stromal atrophy |
| Swissprots | P07147 |
| Accessions | CAA42100 CAM22449 CAM22450 CAM22451 EDL31046 P07147 AK148332 BAE28487 AK148370 BAE28511 AK148441 BAE28554 AK177043 AK178803 AK179534 AK180622 AK181833 AK181989 AK184972 AK185619 AK188091 AK189039 AK189488 AK190379 AK190391 AK190422 AK190720 AK190783 AK191129 AK191149 AK191393 AK191462 AK191532 AK191540 AK191697 AK192283 AK192440 AK192857 AK192864 AK192902 AK192907 AK192940 AK193049 AK193585 AK193825 AK193925 AK194119 AK194181 AK194427 AK194480 AK194755 AK194794 AK194981 AK195088 AK195260 AK195566 AK195805 AK195998 AK196132 AK196212 AK196465 AK197240 AK197400 AK197740 AK197855 AK197957 AK198402 AK198477 AK198835 AK198900 AK199149 AK199163 AK199296 AK199330 AK199363 AK199454 AK199510 AK199776 AK199872 AK199962 AK200013 AK200238 AK200321 AK200365 AK200395 AK200845 AK201045 AK201297 AK201323 AK201835 AK201880 AK201909 AK202380 AK202385 AK202735 AK202954 AK202956 AK203101 AK203202 AK203239 AK203316 AK203420 AK203562 AK204044 AK204301 AK204378 AK204415 AK204438 AK204585 AK204597 AK204752 AK204783 AK205230 AK205614 AK205981 AK206598 AK206970 AK207020 AK207203 AK207360 AK207451 AK207664 AK207921 AK207965 AK208194 AK208432 AK208651 AK209040 AK209243 AK209301 AK209365 AK209447 AK209840 AK209886 AK209941 AK210623 AK211654 AK212036 AK212309 AK212393 AK212795 AK213055 AK213314 AK213631 AK213730 AK214061 AK214163 AK214203 AK214877 AK214946 AK215621 AK216615 AK216621 AK216757 AK217145 AK217194 AK217421 AK217687 AK217984 AK218744 AK218840 AK219113 AK219128 AK219226 AK219854 AK219877 AK219958 AK219979 AK219983 AK220030 BC076598 AAH76598 X03687 CAA27323 XM_006537781 XP_006537844 XM_006537782 XP_006537845 XM_006537783 XP_006537846 XM_006537784 XP_006537847 NM_001282014 NP_001268943 NM_001282015 NP_001268944 NM_031202 NP_112479 |
| Function | Oxidation of 5,6-dihydroxyindole-2-carboxylic acid (DHICA) into indole-5,6-quinone-2-carboxylic acid. May regulate or influence the type of melanin synthesized. {ECO:0000269|PubMed:7813420}. |
| Subcellular Location | Melanosome membrane {ECO:0000269|PubMed:17182842}; Single-pass type I membrane protein {ECO:0000269|PubMed:17182842}. Note=Located to mature stage III and IV melanosomes and apposed endosomal tubular membranes. Transported to pigmented melanosomes by the BLOC-1 complex. |
| Tissue Specificity | Pigment cells. |
| Top Pathways | Melanogenesis, Tyrosine metabolism |
Mouse Laminin A / Laminin B ELISA Kit (Sandwich ELISA) - LS-F2494 from LifeSpan Bioscience
|
||||||||||
5, 6-dihydroxyindole-2-carboxylic acid oxidase (TYRP1), Mouse, ELISA Kit - E03T0751 from ARP American Research Products
|
||||||||||
Mouse Nuclear Factor I/B (NFIB) ELISA Kit - EKU06349 from Biomatik
|
||||||||||
Mouse PRSS1(Protease, Serine, 1) ELISA Kit - E-EL-M0964 from Iwai North America Inc.
|
||||||||||
Mouse INHBP (Inhibin Binding Protein) CLIA Kit - E-CL-M0435 from Iwai North America Inc.
|
||||||||||
Mouse Tyrp1 ELISA Kit - E073753 from Biobool
|
||||||||||
Mouse 5,6-dihydroxyindole-2-carboxylic acid oxidase, DHICA oxidase ELISA Kit - EK5053 from Signalway Antibody
|
||||||||||
TYRP1 ELISA Kit (Mouse) (OKEH06531) - OKEH06531 from Aviva Systems Biology
|
||||||||||
Mouse Protease, Serine 1 (PRSS1) ELISA Kit - AE25628MO from ARP American Research Products
|
||||||||||
5, 6-dihydroxyindole-2-carboxylic acid oxidase, DHICA oxidase, ELISA Kit - MBS9428879 from MyBioSource
|